Immunogenicity 7351
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PFN3
Transcript ID
NM_001029886
HLA INFO
A*30:02
TCR INFO
No TCR info found!
Full length protein sequence (137 aa)
MGDWK
1
VYISA
6
VLRDQ
11
RIDDV
16
AIVGH
21
ADNSC
26
VWASR
31
PGGLL
36
AAISP
41
QEVGV
46
LTGPD
51
RHTFL
56
QAGLS
61
VGGRR
66
CCVIR
71
DHLLA
76
EGDGV
81
LDART
86
KGLDA
91
RAVCV
96
GRAPR
101
ALLVL
106
MGRRG
111
VHGGI
116
LNKTV
121
HELIR
126
GLRMQ
131
GA
136
Mutation Information
DNA mutation:
None
Peptide Range:
122 ~ 137
Mut AA position:
134 (13 in Wild Type peptide)
Alignment
Wild Type:
"NKTVHELIRGLRMQGA
||||||||||||.|||
Mutant:
NKTVHELIRGLRIQGA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PFN3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay