Immunogenicity 7372

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
EBLN1
Transcript ID
NM_001199938
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (366 aa)
MSRPR
1
NNPQT
6
SSPQD
11
STKDG
16
SSFHY
21
FQGRF
26
ELSGK
31
SRQYP
36
ADALE
41
PQPGI
46
GDVKV
51
IEKAT
56
KSMLD
61
PAQRS
66
HFYLV
71
TPSLV
76
FLCFI
81
FDGLH
86
KALLS
91
VGVSK
96
RSNIV
101
IGNEN
106
KETGT
111
LYASK
116
FEDVL
121
PTFTA
126
LEMSS
131
ILRHC
136
CDLIG
141
IAAGS
146
SDPIC
151
TNSLQ
156
VQRQF
161
KAMMI
166
SIGRP
171
LHSES
176
ADLLI
181
SYNAG
186
PAIDW
191
INSRP
196
WVGGL
201
MFTFL
206
FGEFE
211
SPACE
216
LLDQV
221
KVVAS
226
KAQMM
231
TYYTV
236
RMFLD
241
QCVDG
246
STALP
251
AVVLE
256
IPVFE
261
QKKPL
266
AKKVL
271
GDFFE
276
FGGVL
281
RHPVI
286
GVLSP
291
QMFPN
296
LATAA
301
NYWAK
306
RRNST
311
FSGFE
316
ALDII
321
PGSTI
326
TFPVL
331
QMASA
336
QKISR
341
GSDMD
346
PYTLN
351
ILRGY
356
GISGF
361
E
366
Mutation Information
DNA mutation:
None
Peptide Range:
13 ~ 37
Mut AA position:
25 (13 in Wild Type peptide)
Alignment
Wild Type:
"PQDSTKDGSSFHYFQGRFELSGKSR
||||||||||||.||||||||||||
Mutant:
PQDSTKDGSSFHCFQGRFELSGKSR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) EBLN1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay