Immunogenicity 7386

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CASP1
Transcript ID
NM_033292
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (404 aa)
MADKV
1
LKEKR
6
KLFIR
11
SMGEG
16
TINGL
21
LDELL
26
QTRVL
31
NKEEM
36
EKVKR
41
ENATV
46
MDKTR
51
ALIDS
56
VIPKG
61
AQACQ
66
ICITY
71
ICEED
76
SYLAG
81
TLGLS
86
ADQTS
91
GNYLN
96
MQDSQ
101
GVLSS
106
FPAPQ
111
AVQDN
116
PAMPT
121
SSGSE
126
GNVKL
131
CSLEE
136
AQRIW
141
KQKSA
146
EIYPI
151
MDKSS
156
RTRLA
161
LIICN
166
EEFDS
171
IPRRT
176
GAEVD
181
ITGMT
186
MLLQN
191
LGYSV
196
DVKKN
201
LTASD
206
MTTEL
211
EAFAH
216
RPEHK
221
TSDST
226
FLVFM
231
SHGIR
236
EGICG
241
KKHSE
246
QVPDI
251
LQLNA
256
IFNML
261
NTKNC
266
PSLKD
271
KPKVI
276
IIQAC
281
RGDSP
286
GVVWF
291
KDSVG
296
VSGNL
301
SLPTT
306
EEFED
311
DAIKK
316
AHIEK
321
DFIAF
326
CSSTP
331
DNVSW
336
RHPTM
341
GSVFI
346
GRLIE
351
HMQEY
356
ACSCD
361
VEEIF
366
RKVRF
371
SFEQP
376
DGRAQ
381
MPTTE
386
RVTLT
391
RCFYL
396
FPGH
401
Mutation Information
DNA mutation:
None
Peptide Range:
334 ~ 358
Mut AA position:
346 (13 in Wild Type peptide)
Alignment
Wild Type:
"TPDNVSWRHPTMGSVFIGRLIEHMQ
||||||||||||.||||||||||||
Mutant:
TPDNVSWRHPTMASVFIGRLIEHMQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CASP1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay