Immunogenicity 7387

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GABRA2
Transcript ID
NM_000807
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (451 aa)
MKTKL
1
NIYNM
6
QFLLF
11
VFLVW
16
DPARL
21
VLANI
26
QEDEA
31
KNNIT
36
IFTRI
41
LDRLL
46
DGYDN
51
RLRPG
56
LGDSI
61
TEVFT
66
NIYVT
71
SFGPV
76
SDTDM
81
EYTID
86
VFFRQ
91
KWKDE
96
RLKFK
101
GPMNI
106
LRLNN
111
LMASK
116
IWTPD
121
TFFHN
126
GKKSV
131
AHNMT
136
MPNKL
141
LRIQD
146
DGTLL
151
YTMRL
156
TVQAE
161
CPMHL
166
EDFPM
171
DAHSC
176
PLKFG
181
SYAYT
186
TSEVT
191
YIWTY
196
NASDS
201
VQVAP
206
DGSRL
211
NQYDL
216
LGQSI
221
GKETI
226
KSSTG
231
EYTVM
236
TAHFH
241
LKRKI
246
GYFVI
251
QTYLP
256
CIMTV
261
ILSQV
266
SFWLN
271
RESVP
276
ARTVF
281
GVTTV
286
LTMTT
291
LSISA
296
RNSLP
301
KVAYA
306
TAMDW
311
FIAVC
316
YAFVF
321
SALIE
326
FATVN
331
YFTKR
336
GWAWD
341
GKSVV
346
NDKKK
351
EKASV
356
MIQNN
361
AYAVA
366
VANYA
371
PNLSK
376
DPVLS
381
TISKS
386
ATTPE
391
PNKKP
396
ENKPA
401
EAKKT
406
FNSVS
411
KIDRM
416
SRIVF
421
PVLFG
426
TFNLV
431
YWATY
436
LNREP
441
VLGVS
446
P
451
Mutation Information
DNA mutation:
None
Peptide Range:
89 ~ 111
Mut AA position:
101 (13 in Wild Type peptide)
Alignment
Wild Type:
"IDVFFRQKWKDERLKFKGPMNIL
||||||||||||.||||||||||
Mutant:
IDVFFRQKWKDEHLKFKGPMNIL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GABRA2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay