Immunogenicity 7397

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CASP1
Transcript ID
NM_033294
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (263 aa)
MADKV
1
LKEKR
6
KLFIR
11
SMGEA
16
PQAVQ
21
DNPAM
26
PTSSG
31
SEGNV
36
KLCSL
41
EEAQR
46
IWKQK
51
SAEIY
56
PIMDK
61
SSRTR
66
LALII
71
CNEEF
76
DSIPR
81
RTGAE
86
VDITG
91
MTMLL
96
QNLGY
101
SVDVK
106
KNLTA
111
SDMTT
116
ELEAF
121
AHRPE
126
HKTSD
131
STFLV
136
FMSHG
141
IREGI
146
CGKKH
151
SEQVP
156
DILQL
161
NAIFN
166
MLNTK
171
NCPSL
176
KDKPK
181
VIIIQ
186
ACRGD
191
NVSWR
196
HPTMG
201
SVFIG
206
RLIEH
211
MQEYA
216
CSCDV
221
EEIFR
226
KVRFS
231
FEQPD
236
GRAQM
241
PTTER
246
VTLTR
251
CFYLF
256
PGH
261
Mutation Information
DNA mutation:
None
Peptide Range:
193 ~ 217
Mut AA position:
205 (13 in Wild Type peptide)
Alignment
Wild Type:
"RGDNVSWRHPTMGSVFIGRLIEHMQ
||||||||||||.||||||||||||
Mutant:
RGDNVSWRHPTMASVFIGRLIEHMQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CASP1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay