Immunogenicity 7426

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
MLXIPL
Transcript ID
NM_032951
HLA INFO
C*03:04
TCR INFO

No TCR info found!

T cell Tumor cell C*03:04
sequence
Full length protein sequence (852 aa)
MAGAL
1
AGLAA
6
GLQVP
11
RVAPS
16
PDSDS
21
DTDSE
26
DPSLR
31
RSAGG
36
LLRSQ
41
VIHSG
46
HFMVS
51
SPHSD
56
SLPRR
61
RDQEG
66
SVGPS
71
DFGPR
76
SIDPT
81
LTRLF
86
ECLSL
91
AYSGK
96
LVSPK
101
WKNFK
106
GLKLL
111
CRDKI
116
RLNNA
121
IWRAW
126
YIQYV
131
KRRKS
136
PVCGF
141
VTPLQ
146
GPEAD
151
AHRKP
156
EAVVL
161
EGNYW
166
KRRIE
171
VVMRE
176
YHKWR
181
IYYKK
186
RLRKP
191
SREDD
196
LLAPK
201
QAEGR
206
WPPPE
211
QWCKQ
216
LFSSV
221
VPVLL
226
GDPEE
231
EPGGR
236
QLLDL
241
NCFLS
246
DISDT
251
LFTMT
256
QSGPS
261
PLQLP
266
PEDAY
271
VGNAD
276
MIQPD
281
LTPLQ
286
PSLDD
291
FMDIS
296
DFFTN
301
SRLPQ
306
PPMPS
311
NFPEP
316
PSFSP
321
VVDSL
326
FSSGT
331
LGPEV
336
PPASS
341
AMTHL
346
SGHSR
351
LQARN
356
SCPGP
361
LDSSA
366
FLSSD
371
FLLPE
376
DPKPR
381
LPPPP
386
VPPPL
391
LHYPP
396
PAKVP
401
GLEPC
406
PPPPF
411
PPMAP
416
PTALL
421
QEEPL
426
FSPRF
431
PFPTV
436
PPAPG
441
VSPLP
446
APAAF
451
PPTPQ
456
SVPSP
461
APTPF
466
PIELL
471
PLGYS
476
EPAFG
481
PCFSM
486
PRGKP
491
PAPSP
496
RGQKA
501
SPPTL
506
APATA
511
SPPTT
516
AGSNN
521
PCLTQ
526
LLTAA
531
KPEQA
536
LEPPL
541
VSSTL
546
LRSPG
551
SPQET
556
VPEFP
561
CTFLP
566
PTPAP
571
TPPRP
576
PPGPA
581
TLAPS
586
RPLLV
591
PKAER
596
LSPPA
601
PSGSE
606
RRLSG
611
DLSSM
616
PGPGT
621
LSVRV
626
SPPQP
631
ILSRG
636
RPDSN
641
KTENR
646
RITHI
651
SAEQK
656
RRFNI
661
KLGFD
666
TLHGL
671
VSTLS
676
AQPSL
681
KVSKA
686
TTLQK
691
TAEYI
696
LMLQQ
701
ERAGL
706
QEEAQ
711
QLRDE
716
IEELN
721
AAINL
726
CQQQL
731
PATGV
736
PITHQ
741
RFDQM
746
RDMFD
751
DYVRT
756
RTLHN
761
WKFWV
766
FSILI
771
RPLFE
776
SFNGM
781
VSTAS
786
VHTLR
791
QTSLA
796
WLDQY
801
CSLPA
806
LRPTV
811
LNSLR
816
QLGTS
821
TSILT
826
DPGRI
831
PEQAT
836
RAVTE
841
GTLGK
846
PL
851
Mutation Information
DNA mutation:
None
Peptide Range:
346 ~ 370
Mut AA position:
358 (13 in Wild Type peptide)
Alignment
Wild Type:
"AMTHLSGHSRLQARNSCPGPLDSSA
||||||||||||.||||||||||||
Mutant:
AMTHLSGHSRLQVRNSCPGPLDSSA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MLXIPL

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay