Immunogenicity 7456

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FMN2
Transcript ID
NM_020066
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (1722 aa)
MGNQD
1
GKLKR
6
SAGDA
11
LHEGG
16
GGAED
21
ALGPR
26
DVEAT
31
KKGSG
36
GKKAL
41
GKHGK
46
GGGGG
51
GGGGE
56
SGKKK
61
SKSDS
66
RASVF
71
SNLRI
76
RKNLS
81
KGKGA
86
GGSRE
91
DVLDS
96
QALQT
101
GELDS
106
AHSLL
111
TKTPD
116
LSLSA
121
DEAGL
126
SDTEC
131
ADPFE
136
VTGPG
141
GPGPA
146
EARVG
151
GRPIA
156
EDVET
161
AAGAQ
166
DGQRT
171
SSGSD
176
TDIYS
181
FHSAT
186
EQEDL
191
LSDIQ
196
QAIRL
201
QQQQQ
206
QQLQL
211
QLQQQ
216
QQQQQ
221
LQGAE
226
EPAAP
231
PTAVS
236
PQPGA
241
FLGLD
246
RFLLG
251
PSGGA
256
GEAPG
261
SPDTE
266
QALSA
271
LSDLP
276
ESLAA
281
EPREP
286
QQPPS
291
PGGLP
296
VSEAP
301
SLPAA
306
QPAAK
311
DSPSS
316
TAFPF
321
PEAGP
326
GEEAA
331
GAPVR
336
GAGDT
341
DEEGE
346
EDAFE
351
DAPRG
356
SPGEE
361
WAPEV
366
GEDAP
371
QRLGE
376
EPEEE
381
AQGPD
386
APAAA
391
SLPGS
396
PAPSQ
401
RCFKP
406
YPLIT
411
PCYIK
416
TTTRQ
421
LSSPN
426
HSPSQ
431
SPNQS
436
PRIKR
441
RPEPS
446
LSRGS
451
RTALA
456
SVAAP
461
AKKHR
466
ADGGL
471
AAGLS
476
RSADW
481
TEELG
486
ARTPR
491
VGGSA
496
HLLER
501
GVASD
506
SGGGV
511
SPALA
516
AKASG
521
APAAA
526
DGFQN
531
VFTGR
536
TLLEK
541
LFSQQ
546
ENGPP
551
EEAEK
556
FCSRI
561
IAMGL
566
LLPFS
571
DCFRE
576
PCNQN
581
AQTNA
586
ASFDQ
591
DQLYT
596
WAAVS
601
QPTHS
606
LDYSE
611
GQFPR
616
RVPSM
621
GPPSK
626
PPDEE
631
HRLED
636
AETES
641
QSAVS
646
ETPQK
651
RSDAV
656
QKEVV
661
DMKSE
666
GQATV
671
IQQLE
676
QTIED
681
LRTKI
686
AELER
691
QYPAL
696
DTEVA
701
SGHQG
706
LENGV
711
TASGD
716
VCLEA
721
LRLEE
726
KEVRH
731
HRILE
736
AKSIQ
741
TSPTE
746
EGGVL
751
TLPPV
756
DGLPG
761
RPPCP
766
PGAES
771
GPQTK
776
FCSEI
781
SLIVS
786
PRRIS
791
VQLDS
796
HQPTQ
801
SISQP
806
PPPPS
811
LLWSA
816
GQGQP
821
GSQPP
826
HSIST
831
EFQTS
836
HEHSV
841
SSAFK
846
NSCNI
851
PSPPP
856
LPCTE
861
SSSSM
866
PGLGM
871
VPPPP
876
PPLPG
881
MTVPT
886
LPSTA
891
IPQPP
896
PLQGT
901
EMLPP
906
PPPPL
911
PGAGI
916
PPPPP
921
LPGAG
926
ILPLP
931
PLPGA
936
GIPPP
941
PPLPG
946
AAIPP
951
PPPLP
956
GAGIP
961
LPPPL
966
PGAGI
971
PPPPP
976
LPGAG
981
IPPPP
986
PLPGA
991
GIPPP
996
PPLPG
1001
AGIPP
1006
PPPLP
1011
GAGIP
1016
PPPPL
1021
PGAGI
1026
PPPPP
1031
LPGAG
1036
IPPPP
1041
PLPGA
1046
GIPPP
1051
PPLPG
1056
AGIPP
1061
PPPLP
1066
GAGIP
1071
PPPPL
1076
PGAGI
1081
PPPPP
1086
LPGAG
1091
IPPPP
1096
PLPGV
1101
GIPPP
1106
PPLPG
1111
AGIPP
1116
PPPLP
1121
GAGIP
1126
PPPPL
1131
PGAGI
1136
PPPPP
1141
LPRVG
1146
IPPPP
1151
PLPGA
1156
GIPPP
1161
PPLPG
1166
AGIPP
1171
PPPLP
1176
GVGIP
1181
PPPPL
1186
PGVGI
1191
PPPPP
1196
LPGAG
1201
IPPPP
1206
PLPGM
1211
GIPPA
1216
PAPPL
1221
PPPGT
1226
GIPPP
1231
PLLPV
1236
SGPPL
1241
LPQVG
1246
SSTLP
1251
TPQVC
1256
GFLPP
1261
PLPSG
1266
LFGLG
1271
MNQDK
1276
GSRKQ
1281
PIEPC
1286
RPMKP
1291
LYWTR
1296
IQLHS
1301
KRDSS
1306
TSLIW
1311
EKIEE
1316
PSIDC
1321
HEFEE
1326
LFSKT
1331
AVKER
1336
KKPIS
1341
DTISK
1346
TKAKQ
1351
VVKLL
1356
SNKRS
1361
QAVGI
1366
LMSSL
1371
HLDMK
1376
DIQHA
1381
VVNLD
1386
NSVVD
1391
LETLQ
1396
ALYEN
1401
RAQSD
1406
ELEKI
1411
EKHGR
1416
SSKDK
1421
ENAKS
1426
LDKPE
1431
QFLYE
1436
LSLIP
1441
NFSER
1446
VFCIL
1451
FQSTF
1456
SESIC
1461
SIRRK
1466
LELLQ
1471
KLCET
1476
LKNGP
1481
GVMQV
1486
LGLVL
1491
AFGNY
1496
MNGGN
1501
KTRGQ
1506
ADGFG
1511
LDILP
1516
KLKDV
1521
KSSDN
1526
SRSLL
1531
SYIVS
1536
YYLRN
1541
FDEDA
1546
GKEQC
1551
LFPLP
1556
EPQDL
1561
FQASQ
1566
MKFED
1571
FQKDL
1576
RKLKK
1581
DLKAC
1586
EVEAG
1591
KVYQV
1596
SSKEH
1601
MQPFK
1606
ENMEQ
1611
FIIQA
1616
KIDQE
1621
AEENS
1626
LTETH
1631
KCFLE
1636
TTAYF
1641
FMKPK
1646
LGEKE
1651
VSPNA
1656
FFSIW
1661
HEFSS
1666
DFKDF
1671
WKKEN
1676
KLLLQ
1681
ERVKE
1686
AEEVC
1691
RQKKG
1696
KSLYK
1701
IKPRH
1706
DSGIK
1711
AKISM
1716
KT
1721
Mutation Information
DNA mutation:
None
Peptide Range:
138 ~ 162
Mut AA position:
150 (13 in Wild Type peptide)
Alignment
Wild Type:
"PFEVTGPGGPGPAEARVGGRPIAED
||||||||||||.||||||||||||
Mutant:
PFEVTGPGGPGPVEARVGGRPIAED"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FMN2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay