Immunogenicity 7512

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MEP1A
Transcript ID
NM_005588
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (746 aa)
MAWIR
1
STCIL
6
FFTLL
11
FAHIA
16
AVPIK
21
YLPEE
26
NVHDA
31
DFGEQ
36
KDISE
41
INLAA
46
GLDLF
51
QGDIL
56
LQKSR
61
NGLRD
66
PNTRW
71
TFPIP
76
YILAD
81
NLGLN
86
AKGAI
91
LYAFE
96
MFRLK
101
SCVDF
106
KPYEG
111
ESSYI
116
IFQQF
121
DGCWS
126
EVGDQ
131
HVGQN
136
ISIGQ
141
GCAYK
146
AIIEH
151
EILHA
156
LGFYH
161
EQSRT
166
DRDDY
171
VNIWW
176
DQILS
181
GYQHN
186
FDTYD
191
DSLIT
196
DLNTP
201
YDYES
206
LMHYQ
211
PFSFN
216
KNASV
221
PTITA
226
KIPEF
231
NSIIG
236
QRLDF
241
SAIDL
246
ERLNR
251
MYNCT
256
TTHTL
261
LDHCT
266
FEKAN
271
ICGMI
276
QGTRD
281
DTDWA
286
HQDSA
291
QAGEV
296
DHTLL
301
GQCTG
306
AGYFM
311
QFSTS
316
SGSAE
321
EAALL
326
ESRIL
331
YPKRK
336
QQCLQ
341
FFYKM
346
TGSPS
351
DRLVV
356
WVRRD
361
DSTGN
366
VRKLV
371
KVQTF
376
QGDDD
381
HNWKI
386
AHVVL
391
KEEQK
396
FRYLF
401
QGTKG
406
DPQNS
411
TGGIY
416
LDDIT
421
LTETP
426
CPTGV
431
WTVRN
436
FSQVL
441
ENTSK
446
GDKLQ
451
SPRFY
456
NSEGY
461
GFGVT
466
LYPNS
471
RESSG
476
YLRLA
481
FHVCS
486
GENDA
491
ILEWP
496
VENRQ
501
VIITI
506
LDQEP
511
DVRNR
516
MSSSM
521
VFTTS
526
KSHTS
531
PAIND
536
TVIWD
541
RPSRV
546
GTYHT
551
DCNCF
556
RSIDL
561
GWSGF
566
ISHQM
571
LKRRS
576
FLKND
581
DLIIF
586
VDFED
591
ITHLS
596
QTEVP
601
TKGKR
606
LSPQG
611
LILQG
616
QEQQV
621
SEEGS
626
GKAML
631
EEALP
636
VSLSQ
641
GQPSR
646
QKRSV
651
ENTGP
656
LEDHN
661
WPQYF
666
RDPCD
671
PNPCQ
676
NDGIC
681
VNVKG
686
MASCR
691
CISGH
696
AFFYT
701
GERCQ
706
AVQVH
711
GSVLG
716
MVIGG
721
TAGVI
726
FLTFS
731
IIAIL
736
SQRPR
741
K
746
Mutation Information
DNA mutation:
None
Peptide Range:
163 ~ 187
Mut AA position:
175 (13 in Wild Type peptide)
Alignment
Wild Type:
"FYHEQSRTDRDDYVNIWWDQILSGY
||||||||||||.||||||||||||
Mutant:
FYHEQSRTDRDDHVNIWWDQILSGY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MEP1A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay