Immunogenicity 7535
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
CDT1
Transcript ID
NM_030928
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (546 aa)
MEQRR
1
VTDFF
6
ARRRP
11
GPPRI
16
APPKL
21
ACRTP
26
SPARP
31
ALRAP
36
ASATS
41
GSRKR
46
ARPPA
51
APGRD
56
QARPP
61
ARRRL
66
RLSVD
71
EVSSP
76
STPEA
81
PDIPA
86
CPSPG
91
QKIKK
96
STPAA
101
GQPPH
106
LTSAQ
111
DQDTI
116
SELAS
121
CLQRA
126
RELGA
131
RVRAL
136
KASAQ
141
DAGES
146
CTPEA
151
EGRPE
156
EPCGE
161
KAPAY
166
QRFHA
171
LAQPG
176
LPGLV
181
LPYKY
186
QVLAE
191
MFRSM
196
DTIVG
201
MLHNR
206
SETPT
211
FAKVQ
216
RGVQD
221
MMRRR
226
FEECN
231
VGQIK
236
TVYPA
241
SYRFR
246
QERSV
251
PTFKD
256
GTRRS
261
DYQLT
266
IEPLL
271
EQEAD
276
GAAPQ
281
LTASR
286
LLQRR
291
QIFSQ
296
KLVEH
301
VKEHH
306
KAFLA
311
SLSPA
316
MVVPE
321
DQLTR
326
WHPRF
331
NVDEV
336
PDIEP
341
AALPQ
346
PPATE
351
KLTTA
356
QEVLA
361
RARNL
366
ISPRM
371
EKALS
376
QLALR
381
SAAPS
386
SPGSP
391
RPALP
396
ATPPA
401
TPPAA
406
SPSAL
411
KGVSQ
416
DLLER
421
IRAKE
426
AQKQL
431
AQMTR
436
CPEQE
441
QRLQR
446
LERLP
451
ELARV
456
LRSVF
461
VSERK
466
PALSM
471
EVACA
476
RMVGS
481
CCTIM
486
SPGEM
491
EKHLL
496
LLSEL
501
LPDWL
506
SLHRI
511
RTDTY
516
VKLDK
521
AADLA
526
HITAR
531
LAHQT
536
RAEEG
541
L
546
Mutation Information
DNA mutation:
None
Peptide Range:
394 ~ 418
Mut AA position:
406 (13 in Wild Type peptide)
Alignment
Wild Type:
"SPRPALPATPPATPPAASPSALKGV
||||||||||||.||||||||||||
Mutant:
SPRPALPATPPAPPPAASPSALKGV"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) CDT1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay