Immunogenicity 7633
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
NRXN2
Transcript ID
NM_015080
HLA INFO
B*13:02
TCR INFO
No TCR info found!
Full length protein sequence (1712 aa)
MASGS
1
RWRPT
6
PPPLL
11
LLLLL
16
ALAAR
21
ADGLE
26
FGGGP
31
GQWAR
36
YARWA
41
GAASS
46
GELSF
51
SLRTN
56
ATRAL
61
LLYLD
66
DGGDC
71
DFLEL
76
LLVDG
81
RLRLR
86
FTLSC
91
AEPAT
96
LQLDT
101
PVADD
106
RWHMV
111
LLTRD
116
ARRTA
121
LAVDG
126
EARAA
131
EVRSK
136
RREMQ
141
VASDL
146
FVGGI
151
PPDVR
156
LSALT
161
LSTVK
166
YEPPF
171
RGLLA
176
NLKLG
181
ERPPA
186
LLGSQ
191
GLRGA
196
TADPL
201
CAPAR
206
NPCAN
211
GGLCT
216
VLAPG
221
EVGCD
226
CSHTG
231
FGGKF
236
CSEEE
241
HPMEG
246
PAHLT
251
LNSEV
256
GSLLF
261
SEGGA
266
GRGGA
271
GDVHQ
276
PTKGK
281
EEFVA
286
TFKGN
291
EFFCY
296
DLSHN
301
PIQSS
306
TDEIT
311
LAFRT
316
LQRNG
321
LMLHT
326
GKSAD
331
YVNLS
336
LKSGA
341
VWLVI
346
NLGSG
351
AFEAL
356
VEPVN
361
GKFND
366
NAWHD
371
VRVTR
376
NLRQH
381
AGIGH
386
AMVNK
391
LHYLV
396
TISVD
401
GILTT
406
TGYTQ
411
EDYTM
416
LGSDD
421
FFYIG
426
GSPNT
431
ADLPG
436
SPVSN
441
NFMGC
446
LKDVV
451
YKNND
456
FKLEL
461
SRLAK
466
EGDPK
471
MKLQG
476
DLSFR
481
CEDVA
486
ALDPV
491
TFESP
496
EAFVA
501
LPRWS
506
AKRTG
511
SISLD
516
FRTTE
521
PNGLL
526
LFSQG
531
RRAGG
536
GAGSH
541
SSAQR
546
ADYFA
551
MELLD
556
GHLYL
561
LLDMG
566
SGGIK
571
LRASS
576
RKVND
581
GEWCH
586
VDFQR
591
DGRKG
596
SISVN
601
SRSTP
606
FLATG
611
DSEIL
616
DLESE
621
LYLGG
626
LPEGG
631
RVDLP
636
LPPEV
641
WTAAL
646
RAGYV
651
GCVRD
656
LFIDG
661
RSRDL
666
RGLAE
671
AQGAV
676
GVAPF
681
CSRET
686
LKQCA
691
SAPCR
696
NGGVC
701
REGWN
706
RFICD
711
CIGTG
716
FLGRV
721
CEREA
726
TVLSY
731
DGSMY
736
MKIML
741
PNAMH
746
TEAED
751
VSLRF
756
MSQRA
761
YGLMM
766
ATTSR
771
ESADT
776
LRLEL
781
DGGQM
786
KLTVN
791
LDCLR
796
VGCAP
801
SKGPE
806
TLFAG
811
HKLND
816
NEWHT
821
VRVVR
826
RGKSL
831
QLSVD
836
NVTVE
841
GQMAG
846
AHMRL
851
EFHNI
856
ETGIM
861
TERRF
866
ISVVP
871
SNFIG
876
HLSGL
881
VFNGQ
886
PYMDQ
891
CKDGD
896
ITYCE
901
LNARF
906
GLRAI
911
VADPV
916
TFKSR
921
SSYLA
926
LATLQ
931
AYASM
936
HLFFQ
941
FKTTA
946
PDGLL
951
LFNSG
956
NGNDF
961
IVIEL
966
VKGYI
971
HYVFD
976
LGNGP
981
SLMKG
986
NSDKP
991
VNDNQ
996
WHNVV
1001
VSRDP
1006
GNVHT
1011
LKIDS
1016
RTVTQ
1021
HSNGA
1026
RNLDL
1031
KGELY
1036
IGGLS
1041
KNMFS
1046
NLPKL
1051
VASRD
1056
GFQGC
1061
LASVD
1066
LNGRL
1071
PDLIA
1076
DALHR
1081
IGQVE
1086
RGCDG
1091
PSTTC
1096
TEESC
1101
ANQGV
1106
CLQQW
1111
DGFTC
1116
DCTMT
1121
SYGGP
1126
VCNDP
1131
GTTYI
1136
FGKGG
1141
ALITY
1146
TWPPN
1151
DRPST
1156
RMDRL
1161
AVGFS
1166
THQRS
1171
AVLVR
1176
VDSAS
1181
GLGDY
1186
LQLHI
1191
DQGTV
1196
GVIFN
1201
VGTDD
1206
ITIDE
1211
PNAIV
1216
SDGKY
1221
HVVRF
1226
TRSGG
1231
NATLQ
1236
VDSWP
1241
VNERY
1246
PAGNF
1251
DNERL
1256
AIARQ
1261
RIPYR
1266
LGRVV
1271
DEWLL
1276
DKGRQ
1281
LTIFN
1286
SQAAI
1291
KIGGR
1296
DQGRP
1301
FQGQV
1306
SGLYY
1311
NGLKV
1316
LALAA
1321
ESDPN
1326
VRTEG
1331
HLRLV
1336
GEGPS
1341
VLLSA
1346
ETTAT
1351
TLLAD
1356
MATTI
1361
METTT
1366
TMATT
1371
TTRRG
1376
RSPTL
1381
RDSTT
1386
QNTDD
1391
LLVAS
1396
AECPS
1401
DDEDL
1406
EECEP
1411
STGGE
1416
LILPI
1421
ITEDS
1426
LDPPP
1431
VATRS
1436
PFVPP
1441
PPTFY
1446
PFLTG
1451
VGATQ
1456
DTLPP
1461
PAARR
1466
PPSGG
1471
PCQAE
1476
RDDSD
1481
CEEPI
1486
EASGF
1491
ASGEV
1496
FDSSL
1501
PPTDD
1506
EDFYT
1511
TFPLV
1516
TDRTT
1521
LLSPR
1526
KPAPR
1531
PNLRT
1536
DGATG
1541
APGVL
1546
FAPSA
1551
PAPNL
1556
PAGKM
1561
NHRDP
1566
LQPLL
1571
ENPPL
1576
GPGAP
1581
TSFEP
1586
RRPPP
1591
LRPGV
1596
TSAPG
1601
FPHLP
1606
TANPT
1611
GPGER
1616
GPPGA
1621
VEVIR
1626
ESSST
1631
TGMVV
1636
GIVAA
1641
AALCI
1646
LILLY
1651
AMYKY
1656
RNRDE
1661
GSYQV
1666
DQSRN
1671
YISNS
1676
AQSNG
1681
AVVKE
1686
KAPAA
1691
PKTPS
1696
KAKKN
1701
KDKEY
1706
YV
1711
Mutation Information
DNA mutation:
None
Peptide Range:
818 ~ 842
Mut AA position:
830 (13 in Wild Type peptide)
Alignment
Wild Type:
"LNDNEWHTVRVVRRGKSLQLSVDNV
||||||||||||.||||||||||||
Mutant:
LNDNEWHTVRVVWRGKSLQLSVDNV"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) NRXN2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay