Immunogenicity 7655

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
AGO3
Transcript ID
NM_024852
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (860 aa)
MEIGS
1
AGPAG
6
AQPLL
11
MVPRR
16
PGYGT
21
MGKPI
26
KLLAN
31
CFQVE
36
IPKID
41
VYLYE
46
VDIKP
51
DKCPR
56
RVNRE
61
VVDSM
66
VQHFK
71
VTIFG
76
DRRPV
81
YDGKR
86
SLYTA
91
NPLPV
96
ATTGV
101
DLDVT
106
LPGEG
111
GKDRP
116
FKVSI
121
KFVSR
126
VSWHL
131
LHEVL
136
TGRTL
141
PEPLE
146
LDKPI
151
STNPV
156
HAVDV
161
VLRHL
166
PSMKY
171
TPVGR
176
SFFSA
181
PEGYD
186
HPLGG
191
GREVW
196
FGFHQ
201
SVRPA
206
MWKMM
211
LNIDV
216
SATAF
221
YKAQP
226
VIQFM
231
CEVLD
236
IHNID
241
EQPRP
246
LTDSH
251
RVKFT
256
KEIKG
261
LKVEV
266
THCGT
271
MRRKY
276
RVCNV
281
TRRPA
286
SHQTF
291
PLQLE
296
NGQTV
301
ERTVA
306
QYFRE
311
KYTLQ
316
LKYPH
321
LPCLQ
326
VGQEQ
331
KHTYL
336
PLEVC
341
NIVAG
346
QRCIK
351
KLTDN
356
QTSTM
361
IKATA
366
RSAPD
371
RQEEI
376
SRLVR
381
SANYE
386
TDPFV
391
QEFQF
396
KVRDE
401
MAHVT
406
GRVLP
411
APMLQ
416
YGGRN
421
RTVAT
426
PSHGV
431
WDMRG
436
KQFHT
441
GVEIK
446
MWAIA
451
CFATQ
456
RQCRE
461
EILKG
466
FTDQL
471
RKISK
476
DAGMP
481
IQGQP
486
CFCKY
491
AQGAD
496
SVEPM
501
FRHLK
506
NTYSG
511
LQLII
516
VILPG
521
KTPVY
526
AEVKR
531
VGDTL
536
LGMAT
541
QCVQV
546
KNVIK
551
TSPQT
556
LSNLC
561
LKINV
566
KLGGI
571
NNILV
576
PHQRP
581
SVFQQ
586
PVIFL
591
GADVT
596
HPPAG
601
DGKKP
606
SIAAV
611
VGSMD
616
AHPSR
621
YCATV
626
RVQRP
631
RQEII
636
QDLAS
641
MVREL
646
LIQFY
651
KSTRF
656
KPTRI
661
IFYRD
666
GVSEG
671
QFRQV
676
LYYEL
681
LAIRE
686
ACISL
691
EKDYQ
696
PGITY
701
IVVQK
706
RHHTR
711
LFCAD
716
RTERV
721
GRSGN
726
IPAGT
731
TVDTD
736
ITHPY
741
EFDFY
746
LCSHA
751
GIQGT
756
SRPSH
761
YHVLW
766
DDNCF
771
TADEL
776
QLLTY
781
QLCHT
786
YVRCT
791
RSVSI
796
PAPAY
801
YAHLV
806
AFRAR
811
YHLVD
816
KEHDS
821
AEGSH
826
VSGQS
831
NGRDP
836
QALAK
841
AVQIH
846
QDTLR
851
TMYFA
856
Mutation Information
DNA mutation:
None
Peptide Range:
327 ~ 351
Mut AA position:
339 (13 in Wild Type peptide)
Alignment
Wild Type:
"PCLQVGQEQKHTYLPLEVCNIVAGQ
||||||||||||.||||||||||||
Mutant:
PCLQVGQEQKHTSLPLEVCNIVAGQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) AGO3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay