Immunogenicity 7668

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
RBM5
Transcript ID
NM_005778
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (815 aa)
MGSDK
1
RVSRT
6
ERSGR
11
YGSII
16
DRDDR
21
DERES
26
RSRRR
31
DSDYK
36
RSSDD
41
RRGDR
46
YDDYR
51
DYDSP
56
ERERE
61
RRNSD
66
RSEDG
71
YHSDG
76
DYGEH
81
DYRHD
86
ISDER
91
ESKTI
96
MLRGL
101
PITIT
106
ESDIR
111
EMMES
116
FEGPQ
121
PADVR
126
LMKRK
131
TGVSR
136
GFAFV
141
EFYHL
146
QDATS
151
WMEAN
156
QKKLV
161
IQGKH
166
IAMHY
171
SNPRP
176
KFEDW
181
LCNKC
186
CLNNF
191
RKRLK
196
CFRCG
201
ADKFD
206
SEQEV
211
PPGTT
216
ESVQS
221
VDYYC
226
DTIIL
231
RNIAP
236
HTVVD
241
SIMTA
246
LSPYA
251
SLAVN
256
NIRLI
261
KDKQT
266
QQNRG
271
FAFVQ
276
LSSAM
281
DASQL
286
LQILQ
291
SLHPP
296
LKIDG
301
KTIGV
306
DFAKS
311
ARKDL
316
VLSDG
321
NRVSA
326
FSVAS
331
TAIAA
336
AQWSS
341
TQSQS
346
GEGGS
351
VDYSY
356
LQPGQ
361
DGYAQ
366
YAQYS
371
QDYQQ
376
FYQQQ
381
AGGLE
386
SDASS
391
ASGTA
396
VTTTS
401
AAVVS
406
QSPQL
411
YNQTS
416
NPPGS
421
PTEEA
426
QPSTS
431
TSTQA
436
PAASP
441
TGVVP
446
GTKYA
451
VPDTS
456
TYQYD
461
ESSGY
466
YYDPT
471
TGLYY
476
DPNSQ
481
YYYNS
486
LTQQY
491
LYWDG
496
EKETY
501
VPAAE
506
SSSHQ
511
QSGLP
516
PAKEG
521
KEKKE
526
KPKSK
531
TAQQI
536
AKDME
541
RWAKS
546
LNKQK
551
ENFKN
556
SFQPV
561
NSLRE
566
EERRE
571
SAAAD
576
AGFAL
581
FEKKG
586
ALAER
591
QQLIP
596
ELVRN
601
GDEEN
606
PLKRG
611
LVAAY
616
SGDSD
621
NEEEL
626
VERLE
631
SEEEK
636
LADWK
641
KMACL
646
LCRRQ
651
FPNKD
656
ALVRH
661
QQLSD
666
LHKQN
671
MDIYR
676
RSRLS
681
EQELE
686
ALELR
691
EREMK
696
YRDRA
701
AERRE
706
KYGIP
711
EPPEP
716
KRKKQ
721
FDAGT
726
VNYEQ
731
PTKDG
736
IDHSN
741
IGNKM
746
LQAMG
751
WREGS
756
GLGRK
761
CQGIT
766
APIEA
771
QVRLK
776
GAGLG
781
AKGSA
786
YGLSG
791
ADSYK
796
DAVRK
801
AMFAR
806
FTEME
811
Mutation Information
DNA mutation:
None
Peptide Range:
420 ~ 444
Mut AA position:
432 (13 in Wild Type peptide)
Alignment
Wild Type:
"SNPPGSPTEEAQPSTSTSTQAPAAS
||||||||||||.||||||||||||
Mutant:
SNPPGSPTEEAQRSTSTSTQAPAAS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RBM5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay