Immunogenicity 7684

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
RNF43
Transcript ID
NM_017763
HLA INFO
B*40:01
TCR INFO

No TCR info found!

T cell Tumor cell B*40:01
sequence
Full length protein sequence (783 aa)
MSGGH
1
QLQLA
6
ALWPW
11
LLMAT
16
LQAGF
21
GRTGL
26
VLAAA
31
VESER
36
SAEQK
41
AIIRV
46
IPLKM
51
DPTGK
56
LNLTL
61
EGVFA
66
GVAEI
71
TPAEG
76
KLMQS
81
HPLYL
86
CNASD
91
DDNLE
96
PGFIS
101
IVKLE
106
SPRRA
111
PRPCL
116
SLASK
121
ARMAG
126
ERGAS
131
AVLFD
136
ITEDR
141
AAAEQ
146
LQQPL
151
GLTWP
156
VVLIW
161
GNDAE
166
KLMEF
171
VYKNQ
176
KAHVR
181
IELKE
186
PPAWP
191
DYDVW
196
ILMTV
201
VGTIF
206
VIILA
211
SVLRI
216
RCRPR
221
HSRPD
226
PLQQR
231
TAWAI
236
SQLAT
241
RRYQA
246
SCRQA
251
RGEWP
256
DSGSS
261
CSSAP
266
VCAIC
271
LEEFS
276
EGQEL
281
RVISC
286
LHEFH
291
RNCVD
296
PWLHQ
301
HRTCP
306
LCMFN
311
ITEGD
316
SFSQS
321
LGPSR
326
SYQEP
331
GRRLH
336
LIRQH
341
PGHAH
346
YHLPA
351
AYLLG
356
PSRSA
361
VARPP
366
RPGPF
371
LPSQE
376
PGMGP
381
RHHRF
386
PRAAH
391
PRAPG
396
EQQRL
401
AGAQH
406
PYAQG
411
WGLSH
416
LQSTS
421
QHPAA
426
CPVPL
431
RRARP
436
PDSSG
441
SGESY
446
CTERS
451
GYLAD
456
GPASD
461
SSSGP
466
CHGSS
471
SDSVV
476
NCTDI
481
SLQGV
486
HGSSS
491
TFCSS
496
LSSDF
501
DPLVY
506
CSPKG
511
DPQRV
516
DMQPS
521
VTSRP
526
RSLDS
531
VVPTG
536
ETQVS
541
SHVHY
546
HRHRH
551
HHYKK
556
RFQWH
561
GRKPG
566
PETGV
571
PQSRP
576
PIPRT
581
QPQPE
586
PPSPD
591
QQVTR
596
SNSAA
601
PSGRL
606
SNPQC
611
PRALP
616
EPAPG
621
PVDAS
626
SICPS
631
TSSLF
636
NLQKS
641
SLSAR
646
HPQRK
651
RRGGP
656
SEPTP
661
GSRPQ
666
DATVH
671
PACQI
676
FPHYT
681
PSVAY
686
PWSPE
691
AHPLI
696
CGPPG
701
LDKRL
706
LPETP
711
GPCYS
716
NSQPV
721
WLCLT
726
PRQPL
731
EPHPP
736
GEGPS
741
EWSSD
746
TAEGR
751
PCPYP
756
HCQVL
761
SAQPG
766
SEEEL
771
EELCE
776
QAV
781
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 25
Mut AA position:
1 (1 in Wild Type peptide)
Alignment
Wild Type:
"MSGGHQLQLAALWPWLLMATLQAGF
.||||||||||||||||||||||||
Mutant:
LSGGHQLQLAALWPWLLMATLQAGF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RNF43

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay