Immunogenicity 77
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
DST
Transcript ID
uc003pdc.4
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (2649 aa)
MHSSS
1
YSYRS
6
SDSVF
11
SNTTS
16
TRTSL
21
DSNEN
26
LLLVH
31
CGPTL
36
INSCI
41
SFGSE
46
SFDGH
51
RLEML
56
QQIAN
61
RVQRD
66
SVICE
71
DKLIL
76
AGNAL
81
QSDSK
86
RLESG
91
VQFQN
96
EAEIA
101
GYILE
106
CENLL
111
RQHVI
116
DVQIL
121
IDGKY
126
YQADQ
131
LVQRV
136
AKLRD
141
EIMAL
146
RNECS
151
SVYSK
156
GRILT
161
TEQTK
166
LMISG
171
ITQSL
176
NSGFA
181
QTLHP
186
SLTSG
191
LTQSL
196
TPSLT
201
SSSMT
206
SGLSS
211
GMTSR
216
LTPSV
221
TPAYT
226
PGFPS
231
GLVPN
236
FSSGV
241
EPNSL
246
QTLKL
251
MQIRK
256
PLLKS
261
SLLDQ
266
NLTEE
271
EINMK
276
FVQDL
281
LNWVD
286
EMQVQ
291
LDRTE
296
WGSDL
301
PSVES
306
HLENH
311
KNVHR
316
AIEEF
321
ESSLK
326
EAKIS
331
EIQMT
336
APLKL
341
TYAEK
346
LHRLE
351
SQYAK
356
LLNTS
361
RNQER
366
HLDTL
371
HNFVS
376
RATNE
381
LIWLN
386
EKEEE
391
EVAYD
396
WSERN
401
TNIAR
406
KKDYH
411
AELMR
416
ELDQK
421
EENIK
426
SVQEI
431
AEQLL
436
LENHP
441
ARLTI
446
EAYRA
451
AMQTQ
456
WSWIL
461
QLCQC
466
VEQHI
471
KENTA
476
YFEFF
481
NDAKE
486
ATDYL
491
RNLKD
496
AIQRK
501
YSCDR
506
SSSIH
511
KLEDL
516
VQESM
521
EEKEE
526
LLQYK
531
STIAN
536
LMGKA
541
KTIIQ
546
LKPRN
551
SDCPL
556
KTSIP
561
IKAIC
566
DYRQI
571
EITIY
576
KDDEC
581
VLANN
586
SHRAK
591
WKVIS
596
PTGNE
601
AMVPS
606
VCFTV
611
PPPNK
616
EAVDL
621
ANRIE
626
QQYQN
631
VLTLW
636
HESHI
641
NMKSV
646
VSWHY
651
LINEI
656
DRIRA
661
SNVAS
666
IKTML
671
PGEHQ
676
QVLSN
681
LQSRF
686
EDFLE
691
DSQES
696
QVFSG
701
SDITQ
706
LEKEV
711
NVCKQ
716
YYQEL
721
LKSAE
726
REEQE
731
ESVYN
736
LYISE
741
VRNIR
746
LRLEN
751
CEDRL
756
IRQIR
761
TPLER
766
DDLHE
771
SVFRI
776
TEQEK
781
LKKEL
786
ERLKD
791
DLGTI
796
TNKCE
801
EFFSQ
806
AAASS
811
SVPTL
816
RSELN
821
VVLQN
826
MNQVY
831
SMSST
836
YIDKL
841
KTVNL
846
VLKNT
851
QAAEA
856
LVKLY
861
ETKLC
866
EEEAV
871
IADKN
876
NIENL
881
ISTLK
886
QWRSE
891
VDEKR
896
QVFHA
901
LEDEL
906
QKAKA
911
ISDEM
916
FKTYK
921
ERDLD
926
FDWHK
931
EKADQ
936
LVERW
941
QNVHV
946
QIDNR
951
LRDLE
956
GIGKS
961
LKYYR
966
DTYHP
971
LDDWI
976
QQVET
981
TQRKI
986
QENQP
991
ENSKT
996
LATQL
1001
NQQKM
1006
LVSEI
1011
EMKQS
1016
KMDEC
1021
QKYAE
1026
QYSAT
1031
VKDYE
1036
LQTMT
1041
YRAMV
1046
DSQQK
1051
SPVKR
1056
RRMQS
1061
SADLI
1066
IQEFM
1071
DLRTR
1076
YTALV
1081
TLMTQ
1086
YIKFA
1091
GDSLK
1096
RLEEE
1101
EIKRC
1106
KETSE
1111
HGAYS
1116
DLLQR
1121
QKATV
1126
LENSK
1131
LTGKI
1136
SELER
1141
MVAEL
1146
KKQKS
1151
RVEEE
1156
LPKVR
1161
EAAEN
1166
ELRKQ
1171
QRNVE
1176
DISLQ
1181
KIRAE
1186
SEAKQ
1191
YRREL
1196
ETIVR
1201
EKEAA
1206
ERELE
1211
RVRQL
1216
TIEAE
1221
AKRAA
1226
VEENL
1231
LNFRN
1236
QLEEN
1241
TFTRR
1246
TLEDH
1251
LKRKD
1256
LSLND
1261
LEQQK
1266
NKLME
1271
ELRRK
1276
RDNEE
1281
ELLKL
1286
IKQME
1291
KDLAF
1296
QKQVA
1301
EKQLK
1306
EKQKI
1311
ELEAR
1316
RKITE
1321
IQYTC
1326
RENAL
1331
PVCPI
1336
TQATS
1341
CRAVT
1346
GLQQE
1351
HDKQK
1356
AEELK
1361
QQVDE
1366
LTAAN
1371
RKAEQ
1376
DMREL
1381
TYELN
1386
ALQLE
1391
KTSSE
1396
EKARL
1401
LKDKL
1406
DETNN
1411
TLRCL
1416
KLELE
1421
RKDQA
1426
EKGYS
1431
QQLRE
1436
LGRQL
1441
NQTTG
1446
KAEEA
1451
MQEAS
1456
DLKKI
1461
KRNYQ
1466
LELES
1471
LNHEK
1476
GKLQR
1481
EVDRI
1486
TRAHA
1491
VAEKN
1496
IQHLN
1501
SQIHS
1506
FRDEK
1511
ELERL
1516
QICQR
1521
KSDHL
1526
KEQFE
1531
KSHEQ
1536
LLQNI
1541
KAEKE
1546
NNDKI
1551
QRLNE
1556
ELEKS
1561
NECAE
1566
MLKQK
1571
VEELT
1576
RQNNE
1581
TKLMM
1586
QRIQA
1591
ESENI
1596
VLEKQ
1601
TIQQR
1606
CEALK
1611
IQADG
1616
FKDQL
1621
RSTNE
1626
HLHKQ
1631
TKTEQ
1636
DFQRK
1641
IKCLE
1646
EDLAK
1651
SQNLV
1656
SEFKQ
1661
KCDQQ
1666
NIIIQ
1671
NTKKE
1676
VRNLN
1681
AELNA
1686
SKEEK
1691
RRGEQ
1696
KVQLQ
1701
QAQVQ
1706
ELNNR
1711
LKKVQ
1716
DELHL
1721
KTIEE
1726
QMTHR
1731
KMVLF
1736
QEESG
1741
KFKQS
1746
AEEFR
1751
KKMEK
1756
LMESK
1761
VITEN
1766
DISGI
1771
RLDFV
1776
SLQQE
1781
NSRAQ
1786
ENAKL
1791
CETNI
1796
KELER
1801
QLQQY
1806
REQMQ
1811
QGQHM
1816
EANHY
1821
QKCQK
1826
LEDEL
1831
IAQKR
1836
EVENL
1841
KQKMD
1846
QQIKE
1851
HEHQL
1856
VLLQC
1861
EIQKK
1866
STAKD
1871
CTFKP
1876
DFEMT
1881
VKECQ
1886
HSGEL
1891
SSRNT
1896
GHLHP
1901
TPRSP
1906
LLRWT
1911
QEPQP
1916
LEEKW
1921
QHRVV
1926
EQIPK
1931
EVQFQ
1936
PPGAP
1941
LEKEK
1946
SQQCY
1951
SEYFS
1956
QTSTE
1961
LQITF
1966
DETNP
1971
ITRLS
1976
EIEKI
1981
RDQAL
1986
NNSRP
1991
PVRYQ
1996
DNACE
2001
MELVK
2006
VLTPL
2011
EIAKN
2016
KQYDM
2021
HTEVT
2026
TLKQE
2031
KNPVP
2036
SAEEW
2041
MLEGC
2046
RASGG
2051
LKKGD
2056
FLKKG
2061
LEPET
2066
FQNFD
2071
GDHAC
2076
SVRDD
2081
EFKFQ
2086
GLRHT
2091
VTARQ
2096
LVEAK
2101
LLDMR
2106
TIEQL
2111
RLGLK
2116
TVEEV
2121
QKTLN
2126
KFLTK
2131
ATSIA
2136
GLYLE
2141
STKEK
2146
ISFAS
2151
AAERI
2156
IIDKM
2161
VALAF
2166
LEAQA
2171
ATGFI
2176
IDPIS
2181
GQTYS
2186
VEDAV
2191
LKGVV
2196
DPEFR
2201
IRLLE
2206
AEKAA
2211
VGYSY
2216
SSKTL
2221
SVFQA
2226
MENRM
2231
LDRQK
2236
GKHIL
2241
EAQIA
2246
SGGVI
2251
DPVRG
2256
IRVPP
2261
EIALQ
2266
QGLLN
2271
NAILQ
2276
FLHEP
2281
SSNTR
2286
VFPNP
2291
NNKQA
2296
LYYSE
2301
LLRMC
2306
VFDVE
2311
SQCFL
2316
FPFGE
2321
RNISN
2326
LNVKK
2331
THRIS
2336
VVDTK
2341
TGSEL
2346
TVYEA
2351
FQRNL
2356
IEKSI
2361
YLELS
2366
GQQYQ
2371
WKEAM
2376
FFESY
2381
GHSSH
2386
MLTDT
2391
KTGLH
2396
FNINE
2401
AIEQG
2406
TIDKA
2411
LVKKY
2416
QEGLI
2421
TLTEL
2426
ADSLL
2431
SRLVP
2436
KKDLH
2441
SPVAG
2446
YWLTA
2451
SGERI
2456
SVLKA
2461
SRRNL
2466
VDRIT
2471
ALRCL
2476
EAQVS
2481
TGGII
2486
DPLTG
2491
KKYRV
2496
AEALH
2501
RGLVD
2506
EGFAQ
2511
QLRQC
2516
ELVIT
2521
GIGHP
2526
ITNKM
2531
MSVVE
2536
AVNAN
2541
IINKE
2546
MGIRC
2551
LEFQY
2556
LTGGL
2561
IEPQV
2566
HSRLS
2571
IEEAL
2576
QVGII
2581
DVLIA
2586
TKLKD
2591
QKSYV
2596
RNIIC
2601
PQTKR
2606
KLTYK
2611
EALEK
2616
ADFDF
2621
HTGLK
2626
LLEVS
2631
EPLMT
2636
GISSL
2641
YYSS
2646
Mutation Information
DNA mutation:
c.C4369A
Peptide Range:
1445 ~ 1469
Mut AA position:
1457 (13 in Wild Type peptide)
Alignment
Wild Type:
"LNQTTGKAEEAMQEASDLKKIKRNY
||||||||||||.||||||||||||
Mutant:
LNQTTGKAEEAMKEASDLKKIKRNY"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) DST
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
LNQTTGKAEEAMKEASDLKKIKRNY
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT