Immunogenicity 779

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PRR36
Transcript ID
ENST00000539422
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (1346 aa)
MDNKR
1
DKAKA
6
GAAAR
11
TPAAR
16
APGLL
21
TPRPP
26
GSPRP
31
PPPVT
36
PAALR
41
VLGAA
46
GAVGR
51
KPLAE
56
RAGGI
61
GGATI
66
PESAP
71
RAGPT
76
RSAGT
81
SSRNP
86
ASRPP
91
ASGRG
96
ERAPP
101
AKNTS
106
PGPVS
111
SPGRA
116
SGTTR
121
PGPLG
126
QKGLR
131
ISAEE
136
TVARG
141
KATEA
146
PKRSA
151
LSAGA
156
RRDTS
161
GPTPG
166
TPSPA
171
MARRS
176
RAAGT
181
EVGLP
186
RPAPS
191
ARPRP
196
PTEGP
201
RKSVS
206
SASEH
211
STTEP
216
SPAAR
221
RRPSA
226
GGGLQ
231
RPASR
236
SLSSS
241
ATPLS
246
SPARS
251
GPSAR
256
GTPRA
261
PAHPS
266
QPKPK
271
GLQAL
276
RPPQV
281
TPPRK
286
DAAPA
291
LGPLS
296
SSPLA
301
TPSPS
306
GTKAR
311
PVPPP
316
DNAAT
321
PLPAT
326
LPPSP
331
PVTPP
336
PPAAL
341
QSQAP
346
PTLPA
351
TPHSS
356
SLTCQ
361
LATPL
366
PLAPP
371
SPSAP
376
PSLQT
381
LPSPP
386
ATPPS
391
QVPPT
396
QLIMS
401
FPEAG
406
VSSLA
411
TAAFV
416
ASVSP
421
SVSSP
426
LQSMP
431
PTQAN
436
PALPS
441
LPTLL
446
SPLAT
451
PPLSA
456
MSPLQ
461
GPVSP
466
ATSLG
471
NSAFP
476
LAALP
481
QPGLS
486
ALTTP
491
PPQAS
496
PSPSP
501
PSLQA
506
TPHTL
511
ATLPL
516
QDSPL
521
LATLP
526
LQASP
531
SPLTT
536
VSLQD
541
PPLVS
546
PSLLA
551
SPPLQ
556
APPHP
561
QAPPS
566
MTTPP
571
MQAPP
576
SLQTI
581
PPIQV
586
PHSLT
591
SPSLQ
596
APPSP
601
LALSS
606
LQATT
611
SLGSP
616
TLQAT
621
HSFLT
626
MSPRQ
631
TQASL
636
ISPSR
641
PASTP
646
PDSPP
651
LQAPL
656
SLPAS
661
PPLQT
666
SLSPA
671
VSPLS
676
SPLTI
681
HPLQA
686
LSSLA
691
SHSPQ
696
APLSS
701
LIMPP
706
LETQS
711
SLAPP
716
SLQTP
721
PASLT
726
TPPLE
731
NLPSL
736
APPPL
741
QTASA
746
PLTTP
751
PLENL
756
PSLAP
761
PPLQT
766
ASAPL
771
TTPHL
776
ETPPC
781
PAPCP
786
LQAPP
791
SPLTT
796
PPPET
801
PSSIA
806
TPPPQ
811
APPAL
816
ASPPL
821
QGLPS
826
PPLSP
831
LATPP
836
PQAPP
841
ALALP
846
PLQAP
851
PSPPA
856
SPPLS
861
PLATP
866
SPQAP
871
NALAV
876
HLLQA
881
PFSPP
886
PSPPV
891
QAPFS
896
PPASP
901
PVSPS
906
ATPPS
911
QAPPS
916
LAAPP
921
LQVPP
926
SPPAS
931
PPMSP
936
SATPP
941
PQAPP
946
PLAAP
951
PLQVP
956
PSPPA
961
SPPMS
966
PSATP
971
PPRVP
976
PLLAA
981
PPLQV
986
PPSPP
991
ASLPM
996
SPLAK
1001
PPPQA
1006
PPALA
1011
TPPLQ
1016
ALPSP
1021
PASFP
1026
GQAPF
1031
SPSAS
1036
LPMSP
1041
LATPP
1046
PQAPP
1051
VLAAP
1056
LLQVP
1061
PSPPA
1066
SPTLQ
1071
APRRP
1076
PTPGP
1081
DTSVS
1086
GPRLT
1091
LALAP
1096
GPPPP
1101
PSRSP
1106
SSTLS
1111
GPDLA
1116
GHSSS
1121
ATSTP
1126
EELRG
1131
YDSGP
1136
EGGAA
1141
ASPPP
1146
DAELA
1151
ACHPA
1156
AWSRG
1161
PAPPL
1166
AFRGA
1171
PGAPL
1176
PWPPA
1181
TGPGS
1186
ADGLC
1191
TIYET
1196
EGPES
1201
ATPAP
1206
GALDP
1211
GPSPG
1216
TSGGK
1221
AAAGA
1226
GAGAS
1231
SRSPK
1236
QARLG
1241
ELPLG
1246
ALQAS
1251
VVQHL
1256
LSRTL
1261
LLAAA
1266
EGAAG
1271
GSGGG
1276
PGGAE
1281
GGGVT
1286
GGARA
1291
ALSDA
1296
ELGRW
1301
AELLS
1306
PLDES
1311
RASIT
1316
SVTSF
1321
SPDDV
1326
ASPQG
1331
DWTVV
1336
EVETF
1341
H
1346
Mutation Information
DNA mutation:
None
Peptide Range:
966 ~ 990
Mut AA position:
978 (13 in Wild Type peptide)
Alignment
Wild Type:
"SPPMSPSATPPPRVPPLLAAPPLQV
||||||||||||.||||||||||||
Mutant:
SPPMSPSATPPPPVPPLLAAPPLQV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000183248

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay