Immunogenicity 793

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SPSB4
Transcript ID
ENST00000310546
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (273 aa)
MGQKL
1
SGSLK
6
SVEVR
11
EPALR
16
PAKRE
21
LRGAE
26
PGRPA
31
RLDQL
36
LDMPA
41
AGLAV
46
QLRHA
51
WNPED
56
RSLNV
61
FVKDD
66
DRLTF
71
HRHPV
76
AQSTD
81
GIRGK
86
VGHAR
91
GLHAW
96
QINWP
101
ARQRG
106
THAVV
111
GVATA
116
RAPLH
121
SVGYT
126
ALVGS
131
DAESW
136
GWDLG
141
RSRLY
146
HDGKN
151
QPGVA
156
YPAFL
161
GPDEA
166
FALPD
171
SLLVV
176
LDMDE
181
GTLSF
186
IVDGQ
191
YLGVA
196
FRGLK
201
GKKLY
206
PVVSA
211
VWGHC
216
EVTMR
221
YINGL
226
DPEPL
231
PLMDL
236
CRRSI
241
RSALG
246
RQRLQ
251
DISSL
256
PLPQS
261
LKNYL
266
QYQ
271
Mutation Information
DNA mutation:
None
Peptide Range:
241 ~ 265
Mut AA position:
253 (13 in Wild Type peptide)
Alignment
Wild Type:
"CRRSIRSALGRQRLQDISSLPLPQS
||||||||||||.||||||||||||
Mutant:
CRRSIRSALGRQCLQDISSLPLPQS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SPSB4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay