Immunogenicity 803

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GLRB
Transcript ID
ENST00000264428
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (497 aa)
MKFLL
1
TTAFL
6
ILISL
11
WVEEA
16
YSKEK
21
SSKKG
26
KGKKK
31
QYLCP
36
SQQSA
41
EDLAR
46
VPANS
51
TSNIL
56
NRLLV
61
SYDPR
66
IRPNF
71
KGIPV
76
DVVVN
81
IFINS
86
FGSIQ
91
ETTMD
96
YRVNI
101
FLRQK
106
WNDPR
111
LKLPS
116
DFRGS
121
DALTV
126
DPTMY
131
KCLWK
136
PDLFF
141
ANEKS
146
ANFHD
151
VTQEN
156
ILLFI
161
FRDGD
166
VLVSM
171
RLSIT
176
LSCPL
181
DLTLF
186
PMDTQ
191
RCKMQ
196
LESFG
201
YTTDD
206
LRFIW
211
QSGDP
216
VQLEK
221
IALPQ
226
FDIKK
231
EDIEY
236
GNCTK
241
YYKGT
246
GYYTC
251
VEVIF
256
TLRRQ
261
VGFYM
266
MGVYA
271
PTLLI
276
VVLSW
281
LSFWI
286
NPDAS
291
AARVP
296
LGIFS
301
VLSLA
306
SECTT
311
LAAEL
316
PKVSY
321
VKALD
326
VWLIA
331
CLLFG
336
FASLV
341
EYAVV
346
QVMLN
351
NPKRV
356
EAEKA
361
RIAKA
366
EQADG
371
KGGNV
376
AKKNT
381
VNGTG
386
TPVHI
391
STLQV
396
GETRC
401
KKVCT
406
SKSDL
411
RSNDF
416
SIVGS
421
LPRDF
426
ELSNY
431
DCYGK
436
PIEVN
441
NGLGK
446
SQAKN
451
NKKPP
456
PAKPV
461
IPTAA
466
KRIDL
471
YARAL
476
FPFCF
481
LFFNV
486
IYWSI
491
YL
496
Mutation Information
DNA mutation:
None
Peptide Range:
423 ~ 447
Mut AA position:
435 (13 in Wild Type peptide)
Alignment
Wild Type:
"VGSLPRDFELSNYDCYGKPIEVNNG
||||||||||||.||||||||||||
Mutant:
VGSLPRDFELSNCDCYGKPIEVNNG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GLRB

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay