Immunogenicity 81
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
INTS6L
Transcript ID
uc004eyw.4
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (857 aa)
MPILL
1
FLIDT
6
SASMN
11
QRTDL
16
GTSYL
21
DIAKG
26
AVELF
31
LKLRA
36
RDPAS
41
RGDRY
46
MLVTY
51
DEPPY
56
CIKAG
61
WKENH
66
ATFMS
71
ELKNL
76
QASGL
81
TTLGQ
86
ALRSS
91
FDLLN
96
LNRLI
101
SGIDN
106
YGQGR
111
NPFFL
116
EPSIL
121
ITITD
126
GNKLT
131
STAGV
136
QEELH
141
LPLNS
146
PLPGS
151
ELTKE
156
PFRWD
161
QRLFA
166
LVLRL
171
PGVAS
176
TEPEQ
181
LGSVP
186
TDESA
191
ITQMC
196
EVTGG
201
RSYCV
206
RTQRM
211
LNQCL
216
ESLVQ
221
KVQSG
226
VVINF
231
EKTGP
236
DPLPI
241
GEDGL
246
MDSSR
251
PSNSF
256
AAQPW
261
HSCHK
266
LIYVR
271
PNSKT
276
GVPVG
281
HWPIP
286
ESFWP
291
DQNLP
296
SLPPR
301
TSHPV
306
VRFSC
311
VDCEP
316
MVIDK
321
LPFDK
326
YELEP
331
SPLTQ
336
YILER
341
KSPHT
346
CWQVF
351
VTSSG
356
KYNEL
361
GYPFG
366
YLKAS
371
TTLTC
376
VNLFV
381
MPYNY
386
PVLLP
391
LLDDL
396
FKVHK
401
LKPNL
406
KWRQA
411
FDSYL
416
KTLPP
421
YYLLT
426
KLESE
431
RILAS
436
VGKKP
441
PQEIG
446
IKVKN
451
HSGGG
456
MSLTH
461
NKNFR
466
KLLKE
471
ITGET
476
ALRLT
481
ELNTK
486
EFAGF
491
QIGLL
496
NKDLK
501
PQTYR
506
NAYDI
511
PRRGL
516
LDQLT
521
RMRSN
526
LLKTH
531
KFIVG
536
QDEDS
541
LHSVP
546
VAQMG
551
NYQEY
556
LKTLA
561
SPLRE
566
IDPDQ
571
PKRLH
576
TFGNP
581
FKQDK
586
KGMMI
591
DEADE
596
FVAGP
601
QNKVK
606
RPGEP
611
NSPMS
616
SKRRR
621
SMSLL
626
LRKPQ
631
TPPTV
636
TNHVG
641
GKGPP
646
SASWF
651
PSYPN
656
LIKPT
661
LVHTD
666
ATIIH
671
DGHEE
676
KMENG
681
QITPD
686
GFLSK
691
SAPSE
696
LINMT
701
GDLMP
706
PNQVD
711
SLSDD
716
FTSLS
721
KDGLI
726
QKPGS
731
NAFVG
736
GAKNC
741
SLSVD
746
DQKDP
751
VASTL
756
GAMPN
761
TLQIT
766
PAMAQ
771
GINAD
776
IKHQL
781
MKEVR
786
KFGRK
791
YERIF
796
ILLEE
801
VQGPL
806
EMKKQ
811
FVEFT
816
IKEAA
821
RFKRR
826
VLIQY
831
LEKRH
836
YKVHL
841
RLPPT
846
SDICS
851
CM
856
Mutation Information
DNA mutation:
c.C592G
Peptide Range:
186 ~ 210
Mut AA position:
None (13 in Wild Type peptide)
Alignment
Wild Type:
"LGSVPTDESAITQMCEVTGGRSYCV
||||||||||||.||||||||||||
Mutant:
LGSVPTDESAITEMCEVTGGRSYCV"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) INTS6L
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
LGSVPTDESAITEMCEVTGGRSYCV
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT