Immunogenicity 814

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
NUP98
Transcript ID
ENST00000355260
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (1726 aa)
MFNKS
1
FGTPF
6
GGGTG
11
GFGTT
16
STFGQ
21
NTGFG
26
TTSGG
31
AFGTS
36
AFGSS
41
NNTGG
46
LFGNS
51
QTKPG
56
GLFGT
61
SSFSQ
66
PATST
71
STGFG
76
FGTST
81
GTANT
86
LFGTA
91
STGTS
96
LFSSQ
101
NNAFA
106
QNKPT
111
GFGNF
116
GTSTS
121
SGGLF
126
GTTNT
131
TSNPF
136
GSTSG
141
SLFGP
146
SSFTA
151
APTGT
156
TIKFN
161
PPTGT
166
DTMVK
171
AGVST
176
NISTK
181
HQCIT
186
AMKEY
191
ESKSL
196
EELRL
201
EDYQA
206
NRKGP
211
QNQVG
216
AGTTT
221
GLFGS
226
SPATS
231
SATGL
236
FSSST
241
TNSGF
246
AYGQN
251
KTAFG
256
TSTTG
261
FGTNP
266
GGLFG
271
QQNQQ
276
TTSLF
281
SKPFG
286
QATTT
291
QNTGF
296
SFGNT
301
STIGQ
306
PSTNT
311
MGLFG
316
VTQAS
321
QPGGL
326
FGTAT
331
NTSTG
336
TAFGT
341
GTGLF
346
GQTNT
351
GFGAV
356
GSTLF
361
GNNKL
366
TTFGS
371
STTSA
376
PSFGT
381
TSGGL
386
FGFGT
391
NTSGN
396
SIFGS
401
KPAPG
406
TLGTG
411
LGAGF
416
GTALG
421
AGQAS
426
LFGNN
431
QPKIG
436
GPLGT
441
GAFGA
446
PGFNT
451
TTATL
456
GFGAP
461
QAPVA
466
LTDPN
471
ASAAQ
476
QAVLQ
481
QHINS
486
LTYSP
491
FGDSP
496
LFRNP
501
MSDPK
506
KKEER
511
LKPTN
516
PAAQK
521
ALTTP
526
THYKL
531
TPRPA
536
TRVRP
541
KALQT
546
TGTAK
551
SHLFD
556
GLDDD
561
EPSLA
566
NGAFM
571
PKKSI
576
KKLVL
581
KNLNN
586
SNLFS
591
PVNRD
596
SENLA
601
SPSEY
606
PENGE
611
RFSFL
616
SKPVD
621
ENHQQ
626
DGDED
631
SLVSH
636
FYTNP
641
IAKPI
646
PQTPE
651
SAGNK
656
HSNSN
661
SVDDT
666
IVALN
671
MRAAL
676
RNGLE
681
GSSEE
686
TSFHD
691
ESLQD
696
DREEI
701
ENNSY
706
HMHPA
711
GIILT
716
KVGYY
721
TIPSM
726
DDLAK
731
ITNEK
736
GECIV
741
SDFTI
746
GRKGY
751
GSIYF
756
EGDVN
761
LTNLN
766
LDDIV
771
HIRRK
776
EVVVY
781
LDDNQ
786
KPPVG
791
EGLNR
796
KAEVT
801
LDGVW
806
PTDKT
811
SRCLI
816
KSPDR
821
LADIN
826
YEGRL
831
EAVSR
836
KQGAQ
841
FKEYR
846
PETGS
851
WVFKV
856
SHFSK
861
YGLQD
866
SDEEE
871
EEHPS
876
KTSTK
881
KLKTA
886
PLPPA
891
SQTTP
896
LQMAL
901
NGKPA
906
PPPQS
911
QSPEV
916
EQLGR
921
VVELD
926
SDMVD
931
ITQEP
936
VLDTM
941
LEESM
946
PEDQE
951
PVSAS
956
THIAS
961
SLGIN
966
PHVLQ
971
IMKAS
976
LLTDE
981
EDVDM
986
ALDQR
991
FSRLP
996
SKADT
1001
SQEIC
1006
SPRLP
1011
ISASH
1016
SSKTR
1021
SLVGG
1026
LLQSK
1031
FTSGA
1036
FLSPS
1041
VSVQE
1046
CRTPR
1051
AASLM
1056
NIPST
1061
SSWSV
1066
PPPLT
1071
SVFTM
1076
PSPAP
1081
EVPLK
1086
TVGTR
1091
RQLGL
1096
VPREK
1101
SVTYG
1106
KGKLL
1111
MDMAL
1116
FMGRS
1121
FRVGW
1126
GPNWT
1131
LANSG
1136
EQLNG
1141
SHELE
1146
NHQIA
1151
DSMEF
1156
GFLPN
1161
PVAVK
1166
PLTES
1171
PFKVH
1176
LEKLS
1181
LRQRK
1186
PDEDM
1191
KLYQT
1196
PLELK
1201
LKHST
1206
VHVDE
1211
LCPLI
1216
VPNLG
1221
VAVIH
1226
DYADW
1231
VKEAS
1236
GDLPE
1241
AQIVK
1246
HWSLT
1251
WTLCE
1256
ALWGH
1261
LKELD
1266
SQLNE
1271
PREYI
1276
QILER
1281
RRAFS
1286
RWLSC
1291
TATPQ
1296
IEEEV
1301
SLTQK
1306
NSPVE
1311
AVFSY
1316
LTGKR
1321
ISEAC
1326
SLAQQ
1331
SGDHR
1336
LALLL
1341
SQFVG
1346
SQSVR
1351
ELLTM
1356
QLVDW
1361
HQLQA
1366
DSFIQ
1371
DERLR
1376
IFALL
1381
AGKPV
1386
WQLSE
1391
KKQIN
1396
VCSQL
1401
DWKRS
1406
LAIHL
1411
WYLLP
1416
PTASI
1421
SRALS
1426
MYEEA
1431
FQNTS
1436
DSDRY
1441
ACSPL
1446
PSYLE
1451
GSGCV
1456
IAEEQ
1461
NSQTP
1466
LRDVC
1471
FHLLK
1476
LYSDS
1481
IREKA
1486
VRELL
1491
TRHCQ
1496
LLETP
1501
ESWAK
1506
ETFLT
1511
QKLRV
1516
PAKWI
1521
HEAKA
1526
VRAHM
1531
ESDKH
1536
LEALC
1541
LFKAE
1546
HWNRC
1551
HKLII
1556
RHLAS
1561
DAIIN
1566
ENYDY
1571
LKGFL
1576
EDLAP
1581
PERSS
1586
LIQDW
1591
ETSGL
1596
VYLDY
1601
IRVIE
1606
MLRHI
1611
QQVDC
1616
SGNDL
1621
EQLHI
1626
KVTSL
1631
CSRIE
1636
QIQCY
1641
SAKDR
1646
LAQSD
1651
MAKRV
1656
ANLLR
1661
VVLSL
1666
HHPPD
1671
RTSDS
1676
TPDPQ
1681
RVPLR
1686
LLAPH
1691
IGRLP
1696
MPEDY
1701
AMDEL
1706
RSLTQ
1711
SYLRE
1716
LAVGS
1721
L
1726
Mutation Information
DNA mutation:
None
Peptide Range:
347 ~ 371
Mut AA position:
359 (13 in Wild Type peptide)
Alignment
Wild Type:
"TGLFGQTNTGFGAVGSTLFGNNKLT
||||||||||||.||||||||||||
Mutant:
TGLFGQTNTGFGDVGSTLFGNNKLT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) NUP98

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay