Immunogenicity 828

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SH3RF3
Transcript ID
ENST00000418513
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (716 aa)
MLLGA
1
SWLCA
6
SKAAA
11
AAAQS
16
EGDED
21
RPGER
26
RRRRA
31
AATAA
36
GAGED
41
MDESS
46
LLDLL
51
ECSVC
56
LERLD
61
TTAKV
66
LPCQH
71
TFCRR
76
CLESI
81
VCSRH
86
ELRCP
91
ECRIL
96
VGCGV
101
DELPA
106
NILLV
111
RLLDG
116
IRQRP
121
RAGTS
126
PGGSP
131
PARPI
136
PGQSA
141
APTLA
146
GGGGG
151
AAGST
156
PGSPV
161
FLSAA
166
AGSTA
171
GSLRE
176
LATSR
181
TAPAA
186
KNPCL
191
LPYGK
196
ALYSY
201
EGKEP
206
GDLKF
211
NKGDI
216
IVLRR
221
KVDEQ
226
WYHGE
231
LHGTQ
236
GFLPA
241
SYIQC
246
IQPLP
251
HAPPQ
256
GKALY
261
DFEMK
266
DKDQD
271
KDCLT
276
FTKDE
281
ILTVL
286
RRVDE
291
NWAEG
296
MLGDK
301
IGIFP
306
LLYVE
311
LNDSA
316
KQLIE
321
MDKPC
326
PAAAS
331
SCNAS
336
LPSDS
341
GAVAS
346
VAPSP
351
TLSSS
356
GAVSA
361
FQRRV
366
DGKKN
371
TKKRH
376
SFTAL
381
SVTHR
386
SSQAA
391
SHRHS
396
MEISA
401
PVLIS
406
SSDPR
411
AAARI
416
GDLAH
421
LSCAA
426
PTQDV
431
SSSAG
436
STPTA
441
VPRAA
446
SVSGE
451
QGTPP
456
KVQLP
461
LNVYL
466
ALYAY
471
KPQKS
476
DELEL
481
HKGEM
486
YRVLE
491
KCQDG
496
WFKGA
501
SLRTG
506
VSGVF
511
PGNYV
516
TPVSR
521
VPAGG
526
AGPPR
531
NNVVG
536
GSPLA
541
KGITT
546
TMHPG
551
SGSLS
556
SLATA
561
TRPAL
566
PITTP
571
QAHAQ
576
HPTAS
581
PPTGS
586
CLRHS
591
AQPTA
596
SQARS
601
TISTA
606
AHSAA
611
QAQDR
616
PTATV
621
SPLRT
626
QNSPS
631
RLPAT
636
SLRPH
641
SVVSP
646
QHSHQ
651
PPVQM
656
CPRPA
661
IPLTS
666
AASAI
671
TPPNV
676
SAANL
681
NGEAG
686
GGPIG
691
VLSTS
696
SPTNT
701
GCKLD
706
EKKSE
711
K
716
Mutation Information
DNA mutation:
None
Peptide Range:
623 ~ 647
Mut AA position:
635 (13 in Wild Type peptide)
Alignment
Wild Type:
"ATVSPLRTQNSPSRLPATSLRPHSV
||||||||||||.||||||||||||
Mutant:
ATVSPLRTQNSPPRLPATSLRPHSV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SH3RF3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay