Immunogenicity 8289

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
EHHADH
Transcript ID
NM_001966
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (723 aa)
MAEYT
1
RLHNA
6
LALIR
11
LRNPP
16
VNAIS
21
TTLLR
26
DIKEG
31
LQKAV
36
IDHTI
41
KAIVI
46
CGAEG
51
KFSAG
56
ADIRG
61
FSAPR
66
TFGLT
71
LGHVV
76
DEIQR
81
NEKPV
86
VAAIQ
91
GMAFG
96
GGLEL
101
ALGCH
106
YRIAH
111
AEAQV
116
GLPEV
121
TLGLL
126
PGARG
131
TQLLP
136
RLTGV
141
PAALD
146
LITSG
151
RRILA
156
DEALK
161
LGILD
166
KVVNS
171
DPVEE
176
AIRFA
181
QRVSD
186
QPLES
191
RRLCN
196
KPIQS
201
LPNMD
206
SIFSE
211
ALLKM
216
RRQHP
221
GCLAQ
226
EACVR
231
AVQAA
236
VQYPY
241
EVGIK
246
KEEEL
251
FLYLL
256
QSGQA
261
RALQY
266
AFFAE
271
RKANK
276
WSTPS
281
GASWK
286
TASAR
291
PVSSV
296
GVVGL
301
GTMGR
306
GIVIS
311
FARAR
316
IPVIA
321
VDSDK
326
NQLAT
331
ANKMI
336
TSVLE
341
KEASK
346
MQQSG
351
HPWSG
356
PKPRL
361
TSSVK
366
ELGGV
371
DLVIE
376
AVFEE
381
MSLKK
386
QVFAE
391
LSAVC
396
KPEAF
401
LCTNT
406
SALDV
411
DEIAS
416
STDRP
421
HLVIG
426
THFFS
431
PAHVM
436
KLLEV
441
IPSQY
446
SSPTT
451
IATVM
456
NLSKK
461
IKKIG
466
VVVGN
471
CFGFV
476
GNRML
481
NPYYN
486
QAYFL
491
LEEGS
496
KPEEV
501
DQVLE
506
EFGFK
511
MGPFR
516
VSDLA
521
GLDVG
526
WKSRK
531
GQGLT
536
GPTLL
541
PGTPA
546
RKRGN
551
RRYCP
556
IPDVL
561
CELGR
566
FGQKT
571
GKGWY
576
QYDKP
581
LGRIH
586
KPDPW
591
LSKFL
596
SRYRK
601
THHIE
606
PRTIS
611
QDEIL
616
ERCLY
621
SLINE
626
AFRIL
631
GEGIA
636
ASPEH
641
IDVVY
646
LHGYG
651
WPRHK
656
GGPMF
661
YASTV
666
GLPTV
671
LEKLQ
676
KYYRQ
681
NPDIP
686
QLEPS
691
DYLKK
696
LASQG
701
NPPLK
706
EWQSL
711
AGSPS
716
SKL
721
Mutation Information
DNA mutation:
None
Peptide Range:
332 ~ 356
Mut AA position:
344 (13 in Wild Type peptide)
Alignment
Wild Type:
"QLATANKMITSVLEKEASKMQQSGH
||||||||||||.||||||||||||
Mutant:
QLATANKMITSVMEKEASKMQQSGH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) EHHADH

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay