Immunogenicity 8300

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
H1FOO
Transcript ID
NM_153833
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (346 aa)
MAPGS
1
VTSDI
6
SPSST
11
STAGS
16
SRSPE
21
SEKPG
26
PSHGG
31
VPPGG
36
PSHSS
41
LPVGR
46
RHPPV
51
LRMVL
56
EALQA
61
GEQRR
66
GTSVA
71
AIKLY
76
ILHKY
81
PTVDV
86
LRFKY
91
LLKQA
96
LATGM
101
RRGLL
106
ARPLN
111
SKARG
116
ATGSF
121
KLVPK
126
HKKKI
131
QPRKM
136
APATA
141
PRRAG
146
EAKGK
151
GPKKP
156
SEAKE
161
DPPNV
166
GKVKK
171
AAKRP
176
AKVQK
181
PPPKP
186
GAATE
191
KARKQ
196
GGAAK
201
DTRAQ
206
SGEAR
211
KVPPK
216
PDKAM
221
RAPSS
226
AGGLS
231
RKAKA
236
KGSRS
241
SQGDA
246
EAYRK
251
TKAES
256
KSSKP
261
TASKV
266
KNGAA
271
SPTKK
276
KVVAK
281
AKAPK
286
AGQGP
291
NTKAA
296
APAKG
301
SGSKV
306
VPAHL
311
SRKTE
316
APKGP
321
RKAGL
326
PIKAS
331
SSKVS
336
SQRAE
341
A
346
Mutation Information
DNA mutation:
None
Peptide Range:
131 ~ 155
Mut AA position:
143 (13 in Wild Type peptide)
Alignment
Wild Type:
"HKKKIQPRKMAPATAPRRAGEAKGK
||||||||||||.||||||||||||
Mutant:
HKKKIQPRKMAPVTAPRRAGEAKGK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) H1FOO

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay