Immunogenicity 8320

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
BRINP2
Transcript ID
NM_021165
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (783 aa)
MRWQC
1
GTRFR
6
GLRPA
11
VAPWT
16
ALLAL
21
GLPGW
26
VLAVS
31
ATAAA
36
VVPEQ
41
HASVA
46
GQHPL
51
DWLLT
56
DRGPF
61
HRAQE
66
YADFM
71
ERYRQ
76
GFTTR
81
YRIYR
86
EFARW
91
KVNNL
96
ALERK
101
DFFSL
106
PLPLA
111
PEFIR
116
NIRLL
121
GRRPN
126
LQQVT
131
ENLIK
136
KYGTH
141
FLLSA
146
TLGGE
151
ESLTI
156
FVDKQ
161
KLGRK
166
TETTG
171
GASII
176
GGSGN
181
STAVS
186
LETLH
191
QLAAS
196
YFIDR
201
ESTLR
206
RLHHI
211
QIATG
216
AIKVT
221
ETRTG
226
PLGCS
231
NYDNL
236
DSVSS
241
VLVQS
246
PENKV
251
QLLGL
256
QVLLP
261
EYLRE
266
RFVAA
271
ALSYI
276
TCSSE
281
GELVC
286
KENDC
291
WCKCS
296
PTFPE
301
CNCPD
306
ADIQA
311
MEDSL
316
LQIQD
321
SWATH
326
NRQFE
331
ESEEF
336
QALLK
341
RLPDD
346
RFLNS
351
TAISQ
356
FWAMD
361
TSLQH
366
RYQQL
371
GAGLK
376
VLFKK
381
THRIL
386
RRLFN
391
LCKRC
396
HRQPR
401
FRLPK
406
ERSLS
411
YWWNR
416
IQSLL
421
YCGES
426
TFPGT
431
FLEQS
436
HSCTC
441
PYDQS
446
SCQGP
451
IPCAL
456
GEGPA
461
CAHCA
466
PDNST
471
RCGSC
476
NPGYV
481
LAQGL
486
CRPEV
491
AESLE
496
NFLGL
501
ETDLQ
506
DLELK
511
YLLQK
516
QDSRI
521
EVHSI
526
FISND
531
MRLGS
536
WFDPS
541
WRKRM
546
LLTLK
551
SNKYK
556
PGLVH
561
VMLAL
566
SLQIC
571
LTKNS
576
TLEPV
581
MAIYV
586
NPFGG
591
SHSES
596
WFMPV
601
NEGSF
606
PDWER
611
TNVDA
616
AAQCQ
621
NWTIT
626
LGNRW
631
KTFFE
636
TVHVY
641
LRSRI
646
KSLDD
651
SSNET
656
IYYEP
661
LEMTD
666
PSKNL
671
GYMKI
676
NTLQV
681
FGYSL
686
PFDPD
691
AIRDL
696
ILQLD
701
YPYTQ
706
GSQDS
711
ALLQL
716
IELRD
721
RVNQL
726
SPPGK
731
VRLDL
736
FSCLL
741
RHRLK
746
LANNE
751
VGRIQ
756
SSLRA
761
FNSKL
766
PNPVE
771
YETGK
776
LCS
781
Mutation Information
DNA mutation:
None
Peptide Range:
339 ~ 363
Mut AA position:
351 (13 in Wild Type peptide)
Alignment
Wild Type:
"EFQALLKRLPDDRFLNSTAISQFWA
||||||||||||.||||||||||||
Mutant:
EFQALLKRLPDDWFLNSTAISQFWA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) BRINP2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay