Immunogenicity 8388

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TMEM260
Transcript ID
NM_017799
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (707 aa)
MSPHG
1
DGRGQ
6
AQGRA
11
VRVGL
16
RRSGG
21
IRGGV
26
AVFAA
31
VAAVF
36
TFTLP
41
PSVPG
46
GDSGE
51
LITAA
56
HELGV
61
AHPPG
66
YPLFT
71
LVAKL
76
AITLF
81
PFGSI
86
AYRVN
91
LLCGL
96
FGAVA
101
ASLLF
106
FTVFR
111
LSGSS
116
AGGIL
121
AAGVF
126
SFSRL
131
TWQWS
136
IAAEV
141
FSLNN
146
LFVGL
151
LMALT
156
VHFEE
161
AATAK
166
ERSKV
171
AKIGA
176
FCCGL
181
SLCNQ
186
HTIIL
191
YVLCI
196
IPWIL
201
FQLLK
206
KKELS
211
LGSLL
216
KLSLY
221
FSAGL
226
LPYVH
231
LPISS
236
YLNHA
241
RWTWG
246
DQTTL
251
QGFLT
256
HFLRE
261
EYGTF
266
SLAKS
271
EIGSS
276
MSEIL
281
LSQVT
286
NMRTE
291
LSFNI
296
QALAV
301
CANIC
306
LATKD
311
RQNPS
316
LVWLF
321
TGMFC
326
IYSLF
331
FAWRA
336
NLDIS
341
KPLFM
346
GVVER
351
FWMQS
356
NAVVA
361
VLAGI
366
GLAAV
371
VSETN
376
RVLNS
381
NGLQC
386
LEWLS
391
ATLFV
396
VYQIY
401
SNYSV
406
CDQRT
411
NYVID
416
KFAKN
421
LLTSM
426
PHDAI
431
ILLRG
436
DLPGN
441
SLRYM
446
HYCEG
451
LRPDI
456
SLVDQ
461
EMMTY
466
EWYLP
471
KMAKH
476
LPGVN
481
FPGNR
486
WNPVE
491
GILPS
496
GMVTF
501
NLYHF
506
LEVNK
511
QKETF
516
VCIGI
521
HEGDP
526
TWKKN
531
YSLWP
536
WGSCD
541
KLVPL
546
EIVFN
551
PEEWI
556
KLTKS
561
IYNWT
566
EEYGR
571
FDPSS
576
WESVA
581
NEEMW
586
QARMK
591
TPFFI
596
FNLAE
601
TAHMP
606
SKVKA
611
QLYAQ
616
AYDLY
621
KEIVY
626
LQKEH
631
PVNWH
636
KNYAI
641
ACERM
646
LRLQA
651
RDADP
656
EVLLS
661
ETIRH
666
FRLYS
671
QKAPN
676
DPQQA
681
DILGA
686
LKHLR
691
KELQS
696
LRNRK
701
NV
706
Mutation Information
DNA mutation:
None
Peptide Range:
553 ~ 577
Mut AA position:
565 (13 in Wild Type peptide)
Alignment
Wild Type:
"VFNPEEWIKLTKSIYNWTEEYGRFD
||||||||||||.||||||||||||
Mutant:
VFNPEEWIKLTKNIYNWTEEYGRFD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TMEM260

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay