Immunogenicity 8398

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
VPS35
Transcript ID
NM_018206
HLA INFO
DQA*01:03 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*06:02
sequence
Full length protein sequence (796 aa)
MPTTQ
1
QSPQD
6
EQEKL
11
LDEAI
16
QAVKV
21
QSFQM
26
KRCLD
31
KNKLM
36
DALKH
41
ASNML
46
GELRT
51
SMLSP
56
KSYYE
61
LYMAI
66
SDELH
71
YLEVY
76
LTDEF
81
AKGRK
86
VADLY
91
ELVQY
96
AGNII
101
PRLYL
106
LITVG
111
VVYVK
116
SFPQS
121
RKDIL
126
KDLVE
131
MCRGV
136
QHPLR
141
GLFLR
146
NYLLQ
151
CTRNI
156
LPDEG
161
EPTDE
166
ETTGD
171
ISDSM
176
DFVLL
181
NFAEM
186
NKLWV
191
RMQHQ
196
GHSRD
201
REKRE
206
RERQE
211
LRILV
216
GTNLV
221
RLSQL
226
EGVNV
231
ERYKQ
236
IVLTG
241
ILEQV
246
VNCRD
251
ALAQE
256
YLMEC
261
IIQVF
266
PDEFH
271
LQTLN
276
PFLRA
281
CAELH
286
QNVNV
291
KNIII
296
ALIDR
301
LALFA
306
HREDG
311
PGIPA
316
DIKLF
321
DIFSQ
326
QVATV
331
IQSRQ
336
DMPSE
341
DVVSL
346
QVSLI
351
NLAMK
356
CYPDR
361
VDYVD
366
KVLET
371
TVEIF
376
NKLNL
381
EHIAT
386
SSAVS
391
KELTR
396
LLKIP
401
VDTYN
406
NILTV
411
LKLKH
416
FHPLF
421
EYFDY
426
ESRKS
431
MSCYV
436
LSNVL
441
DYNTE
446
IVSQD
451
QVDSI
456
MNLVS
461
TLIQD
466
QPDQP
471
VEDPD
476
PEDFA
481
DEQSL
486
VGRFI
491
HLLRS
496
EDPDQ
501
QYLIL
506
NTARK
511
HFGAG
516
GNQRI
521
RFTLP
526
PLVFA
531
AYQLA
536
FRYKE
541
NSKVD
546
DKWEK
551
KCQKI
556
FSFAH
561
QTISA
566
LIKAE
571
LAELP
576
LRLFL
581
QGALA
586
AGEIG
591
FENHE
596
TVAYE
601
FMSQA
606
FSLYE
611
DEISD
616
SKAQL
621
AAITL
626
IIGTF
631
ERMKC
636
FSEEN
641
HEPLR
646
TQCAL
651
AASKL
656
LKKPD
661
QGRAV
666
STCAH
671
LFWSG
676
RNTDK
681
NGEEL
686
HGGKR
691
VMECL
696
KKALK
701
IANQC
706
MDPSL
711
QVQLF
716
IEILN
721
RYIYF
726
YEKEN
731
DAVTI
736
QVLNQ
741
LIQKI
746
REDLP
751
NLESS
756
EETEQ
761
INKHF
766
HNTLE
771
HLRLR
776
RESPE
781
SEGPI
786
YEGLI
791
L
796
Mutation Information
DNA mutation:
None
Peptide Range:
184 ~ 208
Mut AA position:
196 (13 in Wild Type peptide)
Alignment
Wild Type:
"LLNFAEMNKLWVRMQHQGHSRDREK
||||||||||||.||||||||||||
Mutant:
LLNFAEMNKLWVQMQHQGHSRDREK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) VPS35

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay