Immunogenicity 84
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
KCNH7
Transcript ID
uc002uci.3
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1204 aa)
MPVRR
1
GHVAP
6
QNTFL
11
GTIIR
16
KFEGQ
21
NKKFI
26
IANAR
31
VQNCA
36
IIYCN
41
DGFCE
46
MTGFS
51
RPDVM
56
QKPCT
61
CDFLH
66
GPETK
71
RHDIA
76
QIAQA
81
LLGSE
86
ERKVE
91
VTYYH
96
KNGST
101
FICNT
106
HIIPV
111
KNQEG
116
VAMMF
121
IINFE
126
YVTDN
131
ENAAT
136
PERVN
141
PILPI
146
KTVNR
151
KFFGF
156
KFPGL
161
RVLTY
166
RKQSL
171
PQEDP
176
DVVVI
181
DSSKH
186
SDDSV
191
AMKHF
196
KSPTK
201
ESCSP
206
SEADD
211
TKALI
216
QPSKC
221
SPLVN
226
ISGPL
231
DHSSP
236
KRQWD
241
RLYPD
246
MLQSS
251
SQLSH
256
SRSRE
261
SLCSI
266
RRASS
271
VHDIE
276
GFGVH
281
PKNIF
286
RDRHA
291
SEDNG
296
RNVKV
301
SRSWM
306
AGGPF
311
NHIKS
316
SLLGS
321
TSDSN
326
LNKYS
331
TINKI
336
PQLTL
341
NFSEV
346
KTEKK
351
NSSPP
356
SSDKT
361
IIAPK
366
VKDRT
371
HNVTE
376
KVTQV
381
LSLGA
386
DVLPE
391
YKLQT
396
PRINK
401
FTILH
406
YSPFK
411
AVWDW
416
LILLL
421
VIYTA
426
IFTPY
431
SAAFL
436
LNDRE
441
EQKRR
446
ECGYS
451
CSPLN
456
VVDLI
461
VDIMF
466
IIDIL
471
INFRT
476
TYVNQ
481
NEEVV
486
SDPAK
491
IAIHY
496
FKGWF
501
LIDMV
506
AAIPF
511
DLLIF
516
GSGSD
521
ETTTL
526
IGLLK
531
TARLL
536
RLVRV
541
ARKLD
546
RYSEY
551
GAAVL
556
MLLMC
561
IFALI
566
AHWLA
571
CIWYA
576
IGNVE
581
RPYLT
586
DKIGW
591
LDSLG
596
QQIGK
601
RYNDS
606
DSSSG
611
PSIKD
616
KYVTA
621
LYFTF
626
SSLTS
631
VGFGN
636
VSPNT
641
NSEKI
646
FSICV
651
MLIGS
656
LMYAS
661
IFGNV
666
SAIIQ
671
RLYSG
676
TARYH
681
MQMLR
686
VKEFI
691
RFHQI
696
PNPLR
701
QRLEE
706
YFQHA
711
WTYTN
716
GIDMN
721
MVLKG
726
FPECL
731
QADIC
736
LHLNQ
741
TLLQN
746
CKAFR
751
GASKG
756
CLRAL
761
AMKFK
766
TTHAP
771
PGDTL
776
VHCGD
781
VLTAL
786
YFLSR
791
GSIEI
796
LKDDI
801
VVAIL
806
GKNDI
811
FGEMV
816
HLYAK
821
PGKSN
826
ADVRA
831
LTYCD
836
LHKIQ
841
REDLL
846
EVLDM
851
YPEFS
856
DHFLT
861
NLELT
866
FNLRH
871
ESAKA
876
DLLRS
881
QSMND
886
SEGDN
891
CKLRR
896
RKLSF
901
ESEGE
906
KENST
911
NDPED
916
SADTI
921
RHYQS
926
SKRHF
931
EEKKS
936
RSSSF
941
ISSID
946
DEQKP
951
LFSGI
956
VDSSP
961
GIGKA
966
SGLDF
971
EETVP
976
TSGRM
981
HIDKR
986
SHSCK
991
DITDM
996
RSWER
1001
ENAHP
1006
QPEDS
1011
SPSAL
1016
QRAAW
1021
GISET
1026
ESDLT
1031
YGEVE
1036
QRLDL
1041
LQEQL
1046
NRLES
1051
QMTTD
1056
IQTIL
1061
QLLQK
1066
QTTVV
1071
PPAYS
1076
MVTAG
1081
SEYQR
1086
PIIQL
1091
MRTSQ
1096
PEASI
1101
KTDRS
1106
FSPSS
1111
QCPEF
1116
LDLEK
1121
SKLKS
1126
KESLS
1131
SGVHL
1136
NTASE
1141
DNLTS
1146
LLKQD
1151
SDLSL
1156
ELHLR
1161
QRKTY
1166
VHPIR
1171
HPSLP
1176
DSSLS
1181
TVGIV
1186
GLHRH
1191
VSDPG
1196
LPGK
1201
Mutation Information
DNA mutation:
c.A482C
Peptide Range:
149 ~ 173
Mut AA position:
161 (13 in Wild Type peptide)
Alignment
Wild Type:
"PIKTVNRKFFGFKFPGLRVLTYRKQ
||||||||||||.||||||||||||
Mutant:
PIKTVNRKFFGFTFPGLRVLTYRKQ"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) KCNH7
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
PIKTVNRKFFGFTFPGLRVLTYRKQ
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT