Immunogenicity 840

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
DPP3
Transcript ID
ENST00000453114
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (737 aa)
MADTQ
1
YILPN
6
DIGVS
11
SLDCR
16
EAFRL
21
LSPTE
26
RLYAY
31
HLSRA
36
AWYGG
41
LAVLL
46
QTSPE
51
APYIY
56
ALLSR
61
LFRAQ
66
DPDQL
71
RQHAL
76
AEGLT
81
EEEYQ
86
AFLVY
91
AAGVY
96
SNMGN
101
YKSFG
106
DTKFV
111
PNLPK
116
EKLER
121
VILGS
126
EAAQQ
131
HPEEV
136
RGLWQ
141
TCGEL
146
MFSLE
151
PRLRH
156
LGLGK
161
EGITT
166
YFSGN
171
CTMED
176
AKLAQ
181
DFLDS
186
QNLSA
191
YNTRL
196
FKEVD
201
GEGKP
206
YYEVR
211
LASVL
216
GSEPS
221
LDSEV
226
TSKLK
231
SYEFR
236
GSPFQ
241
VTRGD
246
YAPIL
251
QKVVE
256
QLEKA
261
KAYAA
266
NSHQG
271
QMLAQ
276
YIESF
281
TQGSI
286
EAHKR
291
GSRFW
296
IQDKG
301
PIVES
306
YIGFI
311
ESYRD
316
PFGSR
321
GEFEG
326
FVAVV
331
NKAMS
336
AKFER
341
LVASA
346
EQLLK
351
ELPWP
356
PTFEK
361
DKFLT
366
PDFTS
371
LDVLT
376
FAGSG
381
IPAGI
386
NIPNY
391
DDLRQ
396
TEGFK
401
NVSLG
406
NVLAV
411
AYATQ
416
REKLT
421
FLEED
426
DKDLY
431
ILWKG
436
PSFDV
441
QVGLH
446
ELLGH
451
GSGKL
456
FVQDE
461
KGAFN
466
FDQET
471
VINPE
476
TGEQI
481
QSWYR
486
SGETW
491
DSKFS
496
TIASS
501
YEECR
506
AESVG
511
LYLCL
516
HPQVL
521
EIFGF
526
EGADA
531
EDVIY
536
VNWLN
541
MVRAG
546
LLALE
551
FYTPE
556
AFNWR
561
QAHMQ
566
ARFVI
571
LRVLL
576
EAGEG
581
LVTIT
586
PTTGS
591
DGRPD
596
ARVRL
601
DRSKI
606
RSVGK
611
PALER
616
FLRRL
621
QVLKS
626
TGDVA
631
GGRAL
636
YEGYA
641
TVTDA
646
PPECF
651
LTLRD
656
TVLLR
661
KESRK
666
LIVQP
671
NTRLE
676
GSDVQ
681
LLEYE
686
ASAAG
691
LIRSF
696
SERFP
701
EDGPE
706
LEEIL
711
TQLAT
716
ADARF
721
WKGPS
726
EAPSG
731
QA
736
Mutation Information
DNA mutation:
None
Peptide Range:
370 ~ 394
Mut AA position:
382 (13 in Wild Type peptide)
Alignment
Wild Type:
"TPDFTSLDVLTFAGSGIPAGINIPN
||||||||||||.||||||||||||
Mutant:
TPDFTSLDVLTFVGSGIPAGINIPN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DPP3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay