Immunogenicity 8522

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ADAM9
Transcript ID
NM_003816
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (819 aa)
MGSGA
1
RFPSG
6
TLRVR
11
WLLLL
16
GLVGP
21
VLGAA
26
RPGFQ
31
QTSHL
36
SSYEI
41
ITPWR
46
LTRER
51
REAPR
56
PYSKQ
61
VSYVI
66
QAEGK
71
EHIIH
76
LERNK
81
DLLPE
86
DFVVY
91
TYNKE
96
GTLIT
101
DHPNI
106
QNHCH
111
YRGYV
116
EGVHN
121
SSIAL
126
SDCFG
131
LRGLL
136
HLENA
141
SYGIE
146
PLQNS
151
SHFEH
156
IIYRM
161
DDVYK
166
EPLKC
171
GVSNK
176
DIEKE
181
TAKDE
186
EEEPP
191
SMTQL
196
LRRRR
201
AVLPQ
206
TRYVE
211
LFIVV
216
DKERY
221
DMMGR
226
NQTAV
231
REEMI
236
LLANY
241
LDSMY
246
IMLNI
251
RIVLV
256
GLEIW
261
TNGNL
266
INIVG
271
GAGDV
276
LGNFV
281
QWREK
286
FLITR
291
RRHDS
296
AQLVL
301
KKGFG
306
GTAGM
311
AFVGT
316
VCSRS
321
HAGGI
326
NVFGQ
331
ITVET
336
FASIV
341
AHELG
346
HNLGM
351
NHDDG
356
RDCSC
361
GAKSC
366
IMNSG
371
ASGSR
376
NFSSC
381
SAEDF
386
EKLTL
391
NKGGN
396
CLLNI
401
PKPDE
406
AYSAP
411
SCGNK
416
LVDAG
421
EECDC
426
GTPKE
431
CELDP
436
CCEGS
441
TCKLK
446
SFAEC
451
AYGDC
456
CKDCR
461
FLPGG
466
TLCRG
471
KTSEC
476
DVPEY
481
CNGSS
486
QFCQP
491
DVFIQ
496
NGYPC
501
QNNKA
506
YCYNG
511
MCQYY
516
DAQCQ
521
VIFGS
526
KAKAA
531
PKDCF
536
IEVNS
541
KGDRF
546
GNCGF
551
SGNEY
556
KKCAT
561
GNALC
566
GKLQC
571
ENVQE
576
IPVFG
581
IVPAI
586
IQTPS
591
RGTKC
596
WGVDF
601
QLGSD
606
VPDPG
611
MVNEG
616
TKCGA
621
GKICR
626
NFQCV
631
DASVL
636
NYDCD
641
VQKKC
646
HGHGV
651
CNSNK
656
NCHCE
661
NGWAP
666
PNCET
671
KGYGG
676
SVDSG
681
PTYNE
686
MNTAL
691
RDGLL
696
VFFFL
701
IVPLI
706
VCAIF
711
IFIKR
716
DQLWR
721
SYFRK
726
KRSQT
731
YESDG
736
KNQAN
741
PSRQP
746
GSVPR
751
HVSPV
756
TPPRE
761
VPIYA
766
NRFAV
771
PTYAA
776
KQPQQ
781
FPSRP
786
PPPQP
791
KVSSQ
796
GNLIP
801
ARPAP
806
APPLY
811
SSLT
816
Mutation Information
DNA mutation:
None
Peptide Range:
459 ~ 483
Mut AA position:
471 (13 in Wild Type peptide)
Alignment
Wild Type:
"DCCKDCRFLPGGTLCRGKTSECDVP
||||||||||||.||||||||||||
Mutant:
DCCKDCRFLPGGSLCRGKTSECDVP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ADAM9

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay