Immunogenicity 8540

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
MTA1
Transcript ID
NM_004689
HLA INFO
C*03:04
TCR INFO

No TCR info found!

T cell Tumor cell C*03:04
sequence
Full length protein sequence (715 aa)
MAANM
1
YRVGD
6
YVYFE
11
NSSSN
16
PYLIR
21
RIEEL
26
NKTAN
31
GNVEA
36
KVVCF
41
YRRRD
46
ISSTL
51
IALAD
56
KHATL
61
SVCYK
66
AGPGA
71
DNGEE
76
GEIEE
81
EMENP
86
EMVDL
91
PEKLK
96
HQLRH
101
RELFL
106
SRQLE
111
SLPAT
116
HIRGK
121
CSVTL
126
LNETE
131
SLKSY
136
LERED
141
FFFYS
146
LVYDP
151
QQKTL
156
LADKG
161
EIRVG
166
NRYQA
171
DITDL
176
LKEGE
181
EDGRD
186
QSRLE
191
TQVWE
196
AHNPL
201
TDKQI
206
DQFLV
211
VARSV
216
GTFAR
221
ALDCS
226
SSVRQ
231
PSLHM
236
SAAAA
241
SRDIT
246
LFHAM
251
DTLHK
256
NIYDI
261
SKAIS
266
ALVPQ
271
GGPVL
276
CRDEM
281
EEWSA
286
SEANL
291
FEEAL
296
EKYGK
301
DFTDI
306
QQDFL
311
PWKSL
316
TSIIE
321
YYYMW
326
KTTDR
331
YVQQK
336
RLKAA
341
EAESK
346
LKQVY
351
IPNYN
356
KPNPN
361
QISVN
366
NVKAG
371
VVNGT
376
GAPGQ
381
SPGAG
386
RACES
391
CYTTQ
396
SYQWY
401
SWGPP
406
NMQCR
411
LCASC
416
WTYWK
421
KYGGL
426
KMPTR
431
LDGER
436
PGPNR
441
SNMSP
446
HGLPA
451
RSSGS
456
PKFAM
461
KTRQA
466
FYLHT
471
TKLTR
476
IARRL
481
CREIL
486
RPWHA
491
ARHPY
496
LPINS
501
AAIKA
506
ECTAR
511
LPEAS
516
QSPLV
521
LKQAV
526
RKPLE
531
AVLRY
536
LETHP
541
RPPKP
546
DPVKS
551
VSSVL
556
SSLTP
561
AKVAP
566
VINNG
571
SPTIL
576
GKRSY
581
EQHNG
586
VDGNM
591
KKRLL
596
MPSRG
601
LANHG
606
QARHM
611
GPSRN
616
LLLNG
621
KSYPT
626
KVRLI
631
RGGSL
636
PPVKR
641
RRMNW
646
IDAPD
651
DVFYM
656
ATEET
661
RKIRK
666
LLSSS
671
ETKRA
676
ARRPY
681
KPIAL
686
RQSQA
691
LPPRP
696
PPPAP
701
VNDEP
706
IVIED
711
Mutation Information
DNA mutation:
None
Peptide Range:
534 ~ 558
Mut AA position:
546 (13 in Wild Type peptide)
Alignment
Wild Type:
"LEAVLRYLETHPRPPKPDPVKSVSS
||||||||||||.||||||||||||
Mutant:
LEAVLRYLETHPPPPKPDPVKSVSS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MTA1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay