Immunogenicity 8563

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MYBL2
Transcript ID
NM_002466
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (700 aa)
MSRRT
1
RCEDL
6
DELHY
11
QDTDS
16
DVPEQ
21
RDSKC
26
KVKWT
31
HEEDE
36
QLRAL
41
VRQFG
46
QQDWK
51
FLASH
56
FPNRT
61
DQQCQ
66
YRWLR
71
VLNPD
76
LVKGP
81
WTKEE
86
DQKVI
91
ELVKK
96
YGTKQ
101
WTLIA
106
KHLKG
111
RLGKQ
116
CRERW
121
HNHLN
126
PEVKK
131
SCWTE
136
EEDRI
141
ICEAH
146
KVLGN
151
RWAEI
156
AKMLP
161
GRTDN
166
AVKNH
171
WNSTI
176
KRKVD
181
TGGFL
186
SESKD
191
CKPPV
196
YLLLE
201
LEDKD
206
GLQSA
211
QPTEG
216
QGSLL
221
TNWPS
226
VPPTI
231
KEEEN
236
SEEEL
241
AAATT
246
SKEQE
251
PIGTD
256
LDAVR
261
TPEPL
266
EEFPK
271
REDQE
276
GSPPE
281
TSLPY
286
KWVVE
291
AANLL
296
IPAVG
301
SSLSE
306
ALDLI
311
ESDPD
316
AWCDL
321
SKFDL
326
PEEPS
331
AEDSI
336
NNSLV
341
QLQAS
346
HQQQV
351
LPPRQ
356
PSALV
361
PSVTE
366
YRLDG
371
HTISD
376
LSRSS
381
RGELI
386
PISPS
391
TEVGG
396
SGIGT
401
PPSVL
406
KRQRK
411
RRVAL
416
SPVTE
421
NSTSL
426
SFLDS
431
CNSLT
436
PKSTP
441
VKTLP
446
FSPSQ
451
FLNFW
456
NKQDT
461
LELES
466
PSLTS
471
TPVCS
476
QKVVV
481
TTPLH
486
RDKTP
491
LHQKH
496
AAFVT
501
PDQKY
506
SMDNT
511
PHTPT
516
PFKNA
521
LEKYG
526
PLKPL
531
PQTPH
536
LEEDL
541
KEVLR
546
SEAGI
551
ELIIE
556
DDIRP
561
EKQKR
566
KPGLR
571
RSPIK
576
KVRKS
581
LALDI
586
VDEDV
591
KLMMS
596
TLPKS
601
LSLPT
606
TAPSN
611
SSSLT
616
LSGIK
621
EDNSL
626
LNQGF
631
LQAKP
636
EKAAV
641
AQKPR
646
SHFTT
651
PAPMS
656
SAWKT
661
VACGG
666
TRDQL
671
FMQEK
676
ARQLL
681
GRLKP
686
SHTSR
691
TLILS
696
Mutation Information
DNA mutation:
None
Peptide Range:
548 ~ 572
Mut AA position:
560 (13 in Wild Type peptide)
Alignment
Wild Type:
"VLRSEAGIELIIEDDIRPEKQKRKP
||||||||||||.||||||||||||
Mutant:
VLRSEAGIELIIKDDIRPEKQKRKP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MYBL2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay