Immunogenicity 8567

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
MICALL1
Transcript ID
NM_033386
HLA INFO
C*02:02
TCR INFO

No TCR info found!

T cell Tumor cell C*02:02
sequence
Full length protein sequence (863 aa)
MAGPR
1
GALLA
6
WCRRQ
11
CEGYR
16
GVEIR
21
DLSSS
26
FRDGL
31
AFCAI
36
LHRHR
41
PDLLD
46
FDSLS
51
KDNVF
56
ENNRL
61
AFEVA
66
EKELG
71
IPALL
76
DPNDM
81
VSMSV
86
PDCLS
91
IMTYV
96
SQYYN
101
HFCSP
106
GQAGV
111
SPPRK
116
GLAPC
121
SPPSV
126
APTPV
131
EPEDV
136
AQGEE
141
LSSGS
146
LSEQG
151
TGQTP
156
SSTCA
161
ACQQH
166
VHLVQ
171
RYLAD
176
GRLYH
181
RHCFR
186
CRRCS
191
STLLP
196
GAYEN
201
GPEEG
206
TFVCA
211
EHCAR
216
LGPGT
221
RSGTR
226
PGPFS
231
QPKQQ
236
HQQQL
241
AEDAK
246
DVPGG
251
GPSSS
256
APAGA
261
EADGP
266
KASPE
271
ARPQI
276
PTKPR
281
VPGKL
286
QELAS
291
PPAGR
296
PTPAP
301
RKASE
306
STTPA
311
PPTPR
316
PRSSL
321
QQENL
326
VEQAG
331
SSSLV
336
NGRLH
341
ELPVP
346
KPRGT
351
PKPSE
356
GTPAP
361
RKDPP
366
WITLV
371
QAEPK
376
KKPAP
381
LPPSS
386
SPGPP
391
SQDSR
396
QVENG
401
GTEEV
406
AQPSP
411
TASLE
416
SKPYN
421
PFEEE
426
EEDKE
431
EEAPA
436
APSLA
441
TSPAL
446
GHPES
451
TPKSL
456
HPWYG
461
ITPTS
466
SPKTK
471
KRPAP
476
RAPSA
481
SPLAL
486
HASRL
491
SHSEP
496
PSATP
501
SPALS
506
VESLS
511
SESAS
516
QTAGA
521
ELLEP
526
PAVPK
531
SSSEP
536
AVHAP
541
GTPGN
546
PVSLS
551
TNSSL
556
ASSGE
561
LVEPR
566
VEQMP
571
QASPG
576
LAPRT
581
RGSSG
586
PQPAK
591
PCSGA
596
TPTPL
601
LLVGD
606
RSPVP
611
SPGSS
616
SPQLQ
621
VKSSC
626
KENPF
631
NRKPS
636
PAASP
641
ATKKA
646
TKGSK
651
PVRPP
656
APGHG
661
FPLIK
666
RKVQA
671
DQYIP
676
EEDIH
681
GEMDT
686
IERRL
691
DALEH
696
RGVLL
701
EEKLR
706
GGLNE
711
GREDD
716
MLVDW
721
FKLIH
726
EKHLL
731
VRRES
736
ELIYV
741
FKQQN
746
LEQRQ
751
ADVEY
756
ELRCL
761
LNKPE
766
KDWTE
771
EDRAR
776
EKVLM
781
QELVT
786
LIEQR
791
NAIIN
796
CLDED
801
RQREE
806
EEDKM
811
LEAMI
816
KKKEF
821
QREAE
826
PEGKK
831
KGKFK
836
TMKML
841
KLLGN
846
KRDAK
851
SKSPR
856
DKS
861
Mutation Information
DNA mutation:
None
Peptide Range:
63 ~ 87
Mut AA position:
75 (13 in Wild Type peptide)
Alignment
Wild Type:
"NRLAFEVAEKELGIPALLDPNDMVS
||||||||||||.||||||||||||
Mutant:
NRLAFEVAEKELVIPALLDPNDMVS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MICALL1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay