Immunogenicity 8583

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
GRIA1
Transcript ID
NM_001258023
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (837 aa)
MTYRF
1
CSQFS
6
KGVYA
11
IFGFY
16
ERRTV
21
NMLTS
26
FCGAL
31
HVCFI
36
TPSFP
41
VDTSN
46
QFVLQ
51
LRPEL
56
QDALI
61
SIIDH
66
YKWQK
71
FVYIY
76
DADRG
81
LSVLQ
86
KVLDT
91
AAEKN
96
WQVTA
101
VNILT
106
TTEEG
111
YRMLF
116
QDLEK
121
KKERL
126
VVVDC
131
ESERL
136
NAILG
141
QIIKL
146
EKNGI
151
GYHYI
156
LANLG
161
FMDID
166
LNKFK
171
ESGAN
176
VTGFQ
181
LVNYT
186
DTIPA
191
KIMQQ
196
WKNSD
201
ARDHT
206
RVDWK
211
RPKYT
216
SALTY
221
DGVKV
226
MAEAF
231
QSLRR
236
QRIDI
241
SRRGN
246
AGDCL
251
ANPAV
256
PWGQG
261
IDIQR
266
ALQQV
271
RFEGL
276
TGNVQ
281
FNEKG
286
RRTNY
291
TLHVI
296
EMKHD
301
GIRKI
306
GYWNE
311
DDKFV
316
PAATD
321
AQAGG
326
DNSSV
331
QNRTY
336
IVTTI
341
LEDPY
346
VMLKK
351
NANQF
356
EGNDR
361
YEGYC
366
VELAA
371
EIAKH
376
VGYSY
381
RLEIV
386
SDGKY
391
GARDP
396
DTKAW
401
NGMVG
406
ELVYG
411
RADVA
416
VAPLT
421
ITLVR
426
EEVID
431
FSKPF
436
MSLGI
441
SIMIK
446
KPQKS
451
KPGVF
456
SFLDP
461
LAYEI
466
WMCIV
471
FAYIG
476
VSVVL
481
FLVSR
486
FSPYE
491
WHSEE
496
FEEGR
501
DQTTS
506
DQSNE
511
FGIFN
516
SLWFS
521
LGAFM
526
QQGCD
531
ISPRS
536
LSGRI
541
VGGVW
546
WFFTL
551
IIISS
556
YTANL
561
AAFLT
566
VERMV
571
SPIES
576
AEDLA
581
KQTEI
586
AYGTL
591
EAGST
596
KEFFR
601
RSKIA
606
VFEKM
611
WTYMK
616
SAEPS
621
VFVRT
626
TEEGM
631
IRVRK
636
SKGKY
641
AYLLE
646
STMNE
651
YIEQR
656
KPCDT
661
MKVGG
666
NLDSK
671
GYGIA
676
TPKGS
681
ALRNP
686
VNLAV
691
LKLNE
696
QGLLD
701
KLKNK
706
WWYDK
711
GECGS
716
GGGDS
721
KDKTS
726
ALSLS
731
NVAGV
736
FYILI
741
GGLGL
746
AMLVA
751
LIEFC
756
YKSRS
761
ESKRM
766
KGFCL
771
IPQQS
776
INEAI
781
RTSTL
786
PRNSG
791
AGASS
796
GGSGE
801
NGRVV
806
SHDFP
811
KSMQS
816
IPCMS
821
HSSGM
826
PLGAT
831
GL
836
Mutation Information
DNA mutation:
None
Peptide Range:
774 ~ 798
Mut AA position:
786 (13 in Wild Type peptide)
Alignment
Wild Type:
"CLIPQQSINEAIRTSTLPRNSGAGA
||||||||||||.||||||||||||
Mutant:
CLIPQQSINEAIQTSTLPRNSGAGA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GRIA1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay