Immunogenicity 8590
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MAP3K1
Transcript ID
NM_005921
HLA INFO
B*13:02
TCR INFO
No TCR info found!
Full length protein sequence (1512 aa)
MAAAA
1
GNRAS
6
SSGFP
11
GARAT
16
SPEAG
21
GGGGA
26
LKASS
31
APAAA
36
AGLLR
41
EAGSG
46
GRERA
51
DWRRR
56
QLRKV
61
RSVEL
66
DQLPE
71
QPLFL
76
AASPP
81
ASSTS
86
PSPEP
91
ADAAG
96
SGTGF
101
QPVAV
106
PPPHG
111
AASRG
116
GAHLT
121
ESVAA
126
PDSGA
131
SSPAA
136
AEPGE
141
KRAPA
146
AEPSP
151
AAAPA
156
GREME
161
NKETL
166
KGLHK
171
MDDRP
176
EERMI
181
REKLK
186
ATCMP
191
AWKHE
196
WLERR
201
NRRGP
206
VVVKP
211
IPVKG
216
DGSEM
221
NHLAA
226
ESPGE
231
VQASA
236
ASPAS
241
KGRRS
246
PSPGN
251
SPSGR
256
TVKSE
261
SPGVR
266
RKRVS
271
PVPFQ
276
SGRIT
281
PPRRA
286
PSPDG
291
FSPYS
296
PEETN
301
RRVNK
306
VMRAR
311
LYLLQ
316
QIGPN
321
SFLIG
326
GDSPD
331
NKYRV
336
FIGPQ
341
NCSCA
346
RGTFC
351
IHLLF
356
VMLRV
361
FQLEP
366
SDPML
371
WRKTL
376
KNFEV
381
ESLFQ
386
KYHSR
391
RSSRI
396
KAPSR
401
NTIQK
406
FVSRM
411
SNSHT
416
LSSSS
421
TSTSS
426
SENSI
431
KDEEE
436
QMCPI
441
CLLGM
446
LDEES
451
LTVCE
456
DGCRN
461
KLHHH
466
CMSIW
471
AEECR
476
RNREP
481
LICPL
486
CRSKW
491
RSHDF
496
YSHEL
501
SSPVD
506
SPSSL
511
RAAQQ
516
QTVQQ
521
QPLAG
526
SRRNQ
531
ESNFN
536
LTHYG
541
TQQIP
546
PAYKD
551
LAEPW
556
IQVFG
561
MELVG
566
CLFSR
571
NWNVR
576
EMALR
581
RLSHD
586
VSGAL
591
LLANG
596
ESTGN
601
SGGSS
606
GSSPS
611
GGATS
616
GSSQT
621
SISGD
626
VVEAC
631
CSVLS
636
MVCAD
641
PVYKV
646
YVAAL
651
KTLRA
656
MLVYT
661
PCHSL
666
AERIK
671
LQRLL
676
QPVVD
681
TILVK
686
CADAN
691
SRTSQ
696
LSIST
701
LLELC
706
KGQAG
711
ELAVG
716
REILK
721
AGSIG
726
IGGVD
731
YVLNC
736
ILGNQ
741
TESNN
746
WQELL
751
GRLCL
756
IDRLL
761
LEFPA
766
EFYPH
771
IVSTD
776
VSQAE
781
PVEIR
786
YKKLL
791
SLLTF
796
ALQSI
801
DNSHS
806
MVGKL
811
SRRIY
816
LSSAR
821
MVTTV
826
PHVFS
831
KLLEM
836
LSVSS
841
STHFT
846
RMRRR
851
LMAIA
856
DEVEI
861
AEAIQ
866
LGVED
871
TLDGQ
876
QDSFL
881
QASVP
886
NNYLE
891
TTENS
896
SPECT
901
VHLEK
906
TGKGL
911
CATKL
916
SASSE
921
DISER
926
LASIS
931
VGPSS
936
STTTT
941
TTTTE
946
QPKPM
951
VQTKG
956
RPHSQ
961
CLNSS
966
PLSHH
971
SQLMF
976
PALST
981
PSSST
986
PSVPA
991
GTATD
996
VSKHR
1001
LQGFI
1006
PCRIP
1011
SASPQ
1016
TQRKF
1021
SLQFH
1026
RNCPE
1031
NKDSD
1036
KLSPV
1041
FTQSR
1046
PLPSS
1051
NIHRP
1056
KPSRP
1061
TPGNT
1066
SKQGD
1071
PSKNS
1076
MTLDL
1081
NSSSK
1086
CDDSF
1091
GCSSN
1096
SSNAV
1101
IPSDE
1106
TVFTP
1111
VEEKC
1116
RLDVN
1121
TELNS
1126
SIEDL
1131
LEASM
1136
PSSDT
1141
TVTFK
1146
SEVAV
1151
LSPEK
1156
AENDD
1161
TYKDD
1166
VNHNQ
1171
KCKEK
1176
MEAEE
1181
EEALA
1186
IAMAM
1191
SASQD
1196
ALPIV
1201
PQLQV
1206
ENGED
1211
IIIIQ
1216
QDTPE
1221
TLPGH
1226
TKAKQ
1231
PYRED
1236
TEWLK
1241
GQQIG
1246
LGAFS
1251
SCYQA
1256
QDVGT
1261
GTLMA
1266
VKQVT
1271
YVRNT
1276
SSEQE
1281
EVVEA
1286
LREEI
1291
RMMSH
1296
LNHPN
1301
IIRML
1306
GATCE
1311
KSNYN
1316
LFIEW
1321
MAGGS
1326
VAHLL
1331
SKYGA
1336
FKESV
1341
VINYT
1346
EQLLR
1351
GLSYL
1356
HENQI
1361
IHRDV
1366
KGANL
1371
LIDST
1376
GQRLR
1381
IADFG
1386
AAARL
1391
ASKGT
1396
GAGEF
1401
QGQLL
1406
GTIAF
1411
MAPEV
1416
LRGQQ
1421
YGRSC
1426
DVWSV
1431
GCAII
1436
EMACA
1441
KPPWN
1446
AEKHS
1451
NHLAL
1456
IFKIA
1461
SATTA
1466
PSIPS
1471
HLSPG
1476
LRDVA
1481
LRCLE
1486
LQPQD
1491
RPPSR
1496
ELLKH
1501
PVFRT
1506
TW
1511
Mutation Information
DNA mutation:
None
Peptide Range:
629 ~ 653
Mut AA position:
641 (13 in Wild Type peptide)
Alignment
Wild Type:
"GDVVEACCSVLSMVCADPVYKVYVA
||||||||||||.||||||||||||
Mutant:
GDVVEACCSVLSIVCADPVYKVYVA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) MAP3K1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay