Immunogenicity 8595

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SV2C
Transcript ID
NM_014979
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (727 aa)
MEDSY
1
KDRTS
6
LMKGA
11
KDIAR
16
EVKKQ
21
TVKKV
26
NQAVD
31
RAQDE
36
YTQRS
41
YSRFQ
46
DEEDD
51
DDYYP
56
AGETY
61
NGEAN
66
DDEGS
71
SEATE
76
GHDED
81
DEIYE
86
GEYQG
91
IPSMN
96
QAKDS
101
IVSVG
106
QPKGD
111
EYKDR
116
RELES
121
ERRAD
126
EEELA
131
QQYEL
136
IIQEC
141
GHGRF
146
QWALF
151
FVLGM
156
ALMAD
161
GVEVF
166
VVGFV
171
LPSAE
176
TDLCI
181
PNSGS
186
GWLGS
191
IVYLG
196
MMVGA
201
FFWGG
206
LADKV
211
GRKQS
216
LLICM
221
SVNGF
226
FAFLS
231
SFVQG
236
YGFFL
241
FCRLL
246
SGFGI
251
GGAIP
256
TVFSY
261
FAEVL
266
AREKR
271
GEHLS
276
WLCMF
281
WMIGG
286
IYASA
291
MAWAI
296
IPHYG
301
WSFSM
306
GSAYQ
311
FHSWR
316
VFVIV
321
CALPC
326
VSSVV
331
ALTFM
336
PESPR
341
FLLEV
346
GKHDE
351
AWMIL
356
KLIHD
361
TNMRA
366
RGQPE
371
KVFTV
376
NKIKT
381
PKQID
386
ELIEI
391
ESDTG
396
TWYRR
401
CFVRI
406
RTELY
411
GIWLT
416
FMRCF
421
NYPVR
426
DNTIK
431
LTIVW
436
FTLSF
441
GYYGL
446
SVWFP
451
DVIKP
456
LQSDE
461
YALLT
466
RNVER
471
DKYAN
476
FTINF
481
TMENQ
486
IHTGM
491
EYDNG
496
RFIGV
501
KFKSV
506
TFKDS
511
VFKSC
516
TFEDV
521
TSVNT
526
YFKNC
531
TFIDT
536
VFDNT
541
DFEPY
546
KFIDS
551
EFKNC
556
SFFHN
561
KTGCQ
566
ITFDD
571
DYSAY
576
WIYFV
581
NFLGT
586
LAVLP
591
GNIVS
596
ALLMD
601
RIGRL
606
TMLGG
611
SMVLS
616
GISCF
621
FLWFG
626
TSESM
631
MIGML
636
CLYNG
641
LTISA
646
WNSLD
651
VVTVE
656
LYPTD
661
RRATG
666
FGFLN
671
ALCKA
676
AAVLG
681
NLIFG
686
SLVSI
691
TKSIP
696
ILLAS
701
TVLVC
706
GGLVG
711
LCLPD
716
TRTQV
721
LM
726
Mutation Information
DNA mutation:
None
Peptide Range:
495 ~ 519
Mut AA position:
507 (13 in Wild Type peptide)
Alignment
Wild Type:
"MEYDNGRFIGVKFKSVTFKDSVFKS
||||||||||||.||||||||||||
Mutant:
MEYDNGRFIGVKLKSVTFKDSVFKS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SV2C

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay