Immunogenicity 8621

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF827
Transcript ID
NM_178835
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (1077 aa)
MPRRK
1
QEQPK
6
RLPSH
11
VSRQE
16
EAEGE
21
LSEGE
26
HWYGN
31
SSETP
36
SEASY
41
GEVQE
46
NYKLS
51
LEDRI
56
QEQST
61
SPDTS
66
LGSTT
71
PSSHT
76
LELVA
81
LDSEV
86
LRDSL
91
QCQDH
96
LSPGV
101
SSLCD
106
DDPGS
111
NKPLS
116
SNLRR
121
LLEAG
126
SLKLD
131
AAATA
136
NGRVE
141
SPVNV
146
GSNLS
151
FSPPS
156
HHAQQ
161
LSVLA
166
RKLAE
171
KQEQN
176
DQYTP
181
SNRFI
186
WNQGK
191
WLPNS
196
TTTCS
201
LSPDS
206
AILKL
211
KAAAN
216
AVLQD
221
KSLTR
226
TEETM
231
RFESF
236
SSPFS
241
SQSAS
246
STLAA
251
LSKKV
256
SERSL
261
TPGQE
266
HPPPA
271
SSFLS
276
LASMT
281
SSAAL
286
LKEVA
291
ARAAG
296
SLLAE
301
KSSLL
306
PEDPL
311
PPPPS
316
EKKPE
321
KVTPP
326
PPPPP
331
PPPPP
336
PPPQS
341
LELLL
346
LPVPK
351
GRVSK
356
PSNSA
361
SEEES
366
GKPFQ
371
CPICG
376
LVIKR
381
KSYWK
386
RHMVI
391
HTGLK
396
SHQCP
401
LCPFR
406
CARKD
411
NLKSH
416
MKVHQ
421
HQDRG
426
ETFQC
431
QLCPF
436
TSSRH
441
FSLKL
446
HMRCH
451
QHFLR
456
TEAKV
461
KEEIP
466
DPDVK
471
GSPHL
476
SDSAC
481
LGQQR
486
EGGGT
491
ELVGT
496
MMTSN
501
TPERT
506
SQGGA
511
GVSPL
516
LVKEE
521
PKEDN
526
GLPTS
531
FTLNA
536
ADRPA
541
NHTKL
546
KDPSE
551
YVANS
556
ASALF
561
SQDIS
566
VKMAS
571
DFLMK
576
LSAAN
581
QKEPM
586
NLNFK
591
VKEEP
596
KEGES
601
LSTTL
606
PRSSY
611
VFSPE
616
SEVSA
621
PGVSE
626
DALKP
631
QEGKG
636
SVLRR
641
DVSVK
646
AASEL
651
LMKLS
656
AESYK
661
ETQMV
666
KIKEE
671
PMEVD
676
IQDSH
681
VSISP
686
SRNVG
691
YSTLI
696
GREKT
701
EPLQK
706
MPEGR
711
VPPER
716
NLFSQ
721
DISVK
726
MASEL
731
LFQLS
736
EKVSK
741
EHNHT
746
KENTI
751
RTTTS
756
PFFSE
761
DTFRQ
766
SPFTS
771
NSKEL
776
LPSDS
781
VLHGR
786
ISAPE
791
TEKIV
796
LEAGN
801
GLPSW
806
KFNDQ
811
LFPCD
816
VCGKV
821
FGRQQ
826
TLSRH
831
LSLHT
836
EERKY
841
KCHLC
846
PYAAK
851
CRANL
856
NQHLT
861
VHSVK
866
LVSTD
871
TEDIV
876
SAVTS
881
EGSDG
886
KKHPY
891
YYSCH
896
VCGFE
901
TELNV
906
QFVSH
911
MSLHV
916
DKEQW
921
MFSIC
926
CTACD
931
FVTME
936
EAEIK
941
THIGT
946
KHTGE
951
DRKTP
956
SESNS
961
PSSSS
966
LSALS
971
DSANS
976
KDDSD
981
GSQKN
986
KGGNN
991
LLVIS
996
VMPGS
1001
QPSLN
1006
SEEKP
1011
EKGFE
1016
CVFCN
1021
FVCKT
1026
KNMFE
1031
RHLQI
1036
HLITR
1041
MFECD
1046
VCHKF
1051
MKTPE
1056
QLLEH
1061
KKCHT
1066
VPTGG
1071
LK
1076
Mutation Information
DNA mutation:
None
Peptide Range:
418 ~ 442
Mut AA position:
430 (13 in Wild Type peptide)
Alignment
Wild Type:
"KSHMKVHQHQDRGETFQCQLCPFTS
||||||||||||.||||||||||||
Mutant:
KSHMKVHQHQDRVETFQCQLCPFTS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF827

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay