Immunogenicity 8648
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CTNND1
Transcript ID
NM_001331
HLA INFO
B*18:01
TCR INFO
No TCR info found!
Full length protein sequence (941 aa)
MDDSE
1
VESTA
6
SILAS
11
VKEQE
16
AQFEK
21
LTRAL
26
EEERR
31
HVSAQ
36
LERVR
41
VSPQD
46
ANPLM
51
ANGTL
56
TRRHQ
61
NGRFV
66
GDADL
71
ERQKF
76
SDLKL
81
NGPQD
86
HSHLL
91
YSTIP
96
RMQEP
101
GQIVE
106
TYTEE
111
DPEGA
116
MSVVS
121
VETSD
126
DGTTR
131
RTETT
136
VKKVV
141
KTVTT
146
RTVQP
151
VAMGP
156
DGLPV
161
DASSV
166
SNNYI
171
QTLGR
176
DFRKN
181
GNGGP
186
GPYVG
191
QAGTA
196
TLPRN
201
FHYPP
206
DGYSR
211
HYEDG
216
YPGGS
221
DNYGS
226
LSRVT
231
RIEER
236
YRPSM
241
EGYRA
246
PSRQD
251
VYGPQ
256
PQVRV
261
GGSSV
266
DLHRF
271
HPEPY
276
GLEDD
281
QRSMG
286
YDDLD
291
YGMMS
296
DYGTA
301
RRTGT
306
PSDPR
311
RRLRS
316
YEDMI
321
GEEVP
326
SDQYY
331
WAPLA
336
QHERG
341
SLASL
346
DSLRK
351
GGPPP
356
PNWRQ
361
PELPE
366
VIAML
371
GFRLD
376
AVKSN
381
AAAYL
386
QHLCY
391
RNDKV
396
KTDVR
401
KLKGI
406
PVLVG
411
LLDHP
416
KKEVH
421
LGACG
426
ALKNI
431
SFGRD
436
QDNKI
441
AIKNC
446
DGVPA
451
LVRLL
456
RKARD
461
MDLTE
466
VITGT
471
LWNLS
476
SHDSI
481
KMEIV
486
DHALH
491
ALTDE
496
VIIPH
501
SGWER
506
EPNED
511
CKPRH
516
IEWES
521
VLTNT
526
AGCLR
531
NVSSE
536
RSEAR
541
RKLRE
546
CDGLV
551
DALIF
556
IVQAE
561
IGQKD
566
SDSKL
571
VENCV
576
CLLRN
581
LSYQV
586
HREIP
591
QAERY
596
QEAAP
601
NVANN
606
TGPHA
611
ASCFG
616
AKKGK
621
GKKPI
626
EDPAN
631
DTVDF
636
PKRTS
641
PARGY
646
ELLFQ
651
PEVVR
656
IYISL
661
LKESK
666
TPAIL
671
EASAG
676
AIQNL
681
CAGRW
686
TYGRY
691
IRSAL
696
RQEKA
701
LSAIA
706
DLLTN
711
EHERV
716
VKAAS
721
GALRN
726
LAVDA
731
RNKEL
736
IGKHA
741
IPNLV
746
KNLPG
751
GQQNS
756
SWNFS
761
EDTVI
766
SILNT
771
INEVI
776
AENLE
781
AAKKL
786
RETQG
791
IEKLV
796
LINKS
801
GNRSE
806
KEVRA
811
AALVL
816
QTIWG
821
YKELR
826
KPLEK
831
EGWKK
836
SDFQV
841
NLNNA
846
SRSQS
851
SHSYD
856
DSTLP
861
LIDRN
866
QKSDN
871
NYSTP
876
NERGD
881
HNRTL
886
DRSGD
891
LGDME
896
PLKGT
901
TPLMQ
906
DEGQE
911
SLEEE
916
LDVLV
921
LDDEG
926
GQVSY
931
PSMQK
936
I
941
Mutation Information
DNA mutation:
None
Peptide Range:
49 ~ 73
Mut AA position:
61 (13 in Wild Type peptide)
Alignment
Wild Type:
"QDANPLMANGTLTRRHQNGRFVGDA
||||||||||||.||||||||||||
Mutant:
QDANPLMANGTLPRRHQNGRFVGDA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) CTNND1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay