Immunogenicity 8653

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
USP18
Transcript ID
NM_017414
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (372 aa)
MSKAF
1
GLLRQ
6
ICQSI
11
LAESS
16
QSPAD
21
LEEKK
26
EEDSN
31
MKREQ
36
PRERP
41
RAWDY
46
PHGLV
51
GLHNI
56
GQTCC
61
LNSLI
66
QVFVM
71
NVDFT
76
RILKR
81
ITVPR
86
GADEQ
91
RRSVP
96
FQMLL
101
LLEKM
106
QDSRQ
111
KAVRP
116
LELAY
121
CLQKC
126
NVPLF
131
VQHDA
136
AQLYL
141
KLWNL
146
IKDQI
151
TDVHL
156
VERLQ
161
ALYTI
166
RVKDS
171
LICVD
176
CAMES
181
SRNSS
186
MLTLP
191
LSLFD
196
VDSKP
201
LKTLE
206
DALHC
211
FFQPR
216
ELSSK
221
SKCFC
226
ENCGK
231
KTRGK
236
QVLKL
241
THLPQ
246
TLTIH
251
LMRFS
256
IRNSQ
261
TRKIC
266
HSLYF
271
PQSLD
276
FSQIL
281
PMKRE
286
SCDAE
291
EQSGG
296
QYELF
301
AVIAH
306
VGMAD
311
SGHYC
316
VYIRN
321
AVDGK
326
WFCFN
331
DSNIC
336
LVSWE
341
DIQCT
346
YGNPN
351
YHWQE
356
TAYLL
361
VYMKM
366
EC
371
Mutation Information
DNA mutation:
None
Peptide Range:
313 ~ 337
Mut AA position:
325 (13 in Wild Type peptide)
Alignment
Wild Type:
"MADSGHYCVYIRNAVDGKWFCFNDS
||||||||||||.||||||||||||
Mutant:
MADSGHYCVYIRSAVDGKWFCFNDS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) USP18

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay