Immunogenicity 8670

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZFAND4
Transcript ID
NM_174890
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (727 aa)
MDNRK
1
EPPFF
6
NDDNM
11
GPFYY
16
RLHFC
21
DTMEL
26
FIETL
31
TGTCF
36
ELRVS
41
PFETV
46
ISVKA
51
KIRRL
56
EGIPI
61
CRQHL
66
IWNNM
71
ELEND
76
YCLND
81
YNISE
86
GCTLK
91
LVLAM
96
RGGPI
101
NTRRV
106
PTDDP
111
LRKMA
116
EYLDS
121
SRVEV
126
WEKTS
131
CSKQV
136
TFLVY
141
QEGDQ
146
LNFFP
151
AVDRG
156
DGTLT
161
PLSDS
166
SKKID
171
FHLHV
176
LRRKG
181
EHRMS
186
GGSMY
191
NSDTD
196
EDEET
201
EPSSS
206
GQQII
211
ENSIT
216
MNKMK
221
LLKAK
226
MKNMN
231
LSKKP
236
KKAVK
241
IKPHP
246
PVAPR
251
PSSGS
256
TAPSR
261
HRLLR
266
VLPNI
271
GQSCS
276
PAFGN
281
AYPPE
286
ISRNG
291
ISSLA
296
TQLSA
301
ERYIS
306
SITGE
311
FLKED
316
NSWEN
321
NTLSH
326
FSSNV
331
KLPPQ
336
IPHLE
341
LGNDQ
346
ELADS
351
VLHLG
356
SSLPR
361
QTKHF
366
LGNLP
371
SSNGN
376
IVLPS
381
EECVT
386
EQSLL
391
PKVGS
396
LASFA
401
EGNAD
406
EQSSG
411
LEGAC
416
KVNLE
421
LLLTN
426
ADKGL
431
KAPEQ
436
HLKHV
441
AGVLN
446
GESVE
451
TSVLN
456
YRELS
461
PHKNR
466
LLSPL
471
RCSAP
476
MSLHN
481
SLVKP
486
ERQSK
491
CFEFG
496
KLQPS
501
SSQSL
506
DVQNI
511
TDSSF
516
SRTTC
521
FQGVK
526
VDSLG
531
KRSDV
536
ISKVE
541
ARDIT
546
EMTNK
551
ASKEP
556
VGCVN
561
NISFL
566
ASLAG
571
STSRN
576
RLQST
581
RGAGR
586
LQNSG
591
TGLST
596
NLQHF
601
QEENF
606
RKSSP
611
QLEHT
616
GVFLS
621
THGVG
626
MNGNN
631
AAAGK
636
SVGEC
641
TTHHL
646
PPVKA
651
PLQTK
656
KKTTN
661
HCFLC
666
GKKTG
671
LASSY
676
ECRCG
681
NNFCA
686
SHRYA
691
ETHGC
696
TYDYK
701
SAGRR
706
YLHEA
711
NPVVN
716
APKLP
721
KI
726
Mutation Information
DNA mutation:
None
Peptide Range:
6 ~ 30
Mut AA position:
18 (13 in Wild Type peptide)
Alignment
Wild Type:
"EPPFFNDDNMGPFYYRLHFCDTMEL
||||||||||||.||||||||||||
Mutant:
EPPFFNDDNMGPLYYRLHFCDTMEL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZFAND4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay