Immunogenicity 8675

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
KDM1A
Transcript ID
NM_001009999
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (876 aa)
MLSGK
1
KAAAA
6
AAAAA
11
AAATG
16
TEAGP
21
GTAGG
26
SENGS
31
EVAAQ
36
PAGLS
41
GPAEV
46
GPGAV
51
GERTP
56
RKKEP
61
PRASP
66
PGGLA
71
EPPGS
76
AGPQA
81
GPTVV
86
PGSAT
91
PMETG
96
IAETP
101
EGRRT
106
SRRKR
111
AKVEY
116
REMDE
121
SLANL
126
SEDEY
131
YSEEE
136
RNAKA
141
EKEKK
146
LPPPP
151
PQAPP
156
EEENE
161
SEPEE
166
PSGQA
171
GGLQD
176
DSSGG
181
YGDGQ
186
ASGVE
191
GAAFQ
196
SRLPH
201
DRMTS
206
QEAAC
211
FPDII
216
SGPQQ
221
TQKVF
226
LFIRN
231
RTLQL
236
WLDNP
241
KIQLT
246
FEATL
251
QQLEA
256
PYNSD
261
TVLVH
266
RVHSY
271
LERHG
276
LINFG
281
IYKRI
286
KPLPT
291
KKTGK
296
VIIIG
301
SGVSG
306
LAAAR
311
QLQSF
316
GMDVT
321
LLEAR
326
DRVGG
331
RVATF
336
RKGNY
341
VADLG
346
AMVVT
351
GLGGN
356
PMAVV
361
SKQVN
366
MELAK
371
IKQKC
376
PLYEA
381
NGQAD
386
TVKVP
391
KEKDE
396
MVEQE
401
FNRLL
406
EATSY
411
LSHQL
416
DFNVL
421
NNKPV
426
SLGQA
431
LEVVI
436
QLQEK
441
HVKDE
446
QIEHW
451
KKIVK
456
TQEEL
461
KELLN
466
KMVNL
471
KEKIK
476
ELHQQ
481
YKEAS
486
EVKPP
491
RDITA
496
EFLVK
501
SKHRD
506
LTALC
511
KEYDE
516
LAETQ
521
GKLEE
526
KLQEL
531
EANPP
536
SDVYL
541
SSRDR
546
QILDW
551
HFANL
556
EFANA
561
TPLST
566
LSLKH
571
WDQDD
576
DFEFT
581
GSHLT
586
VRNGY
591
SCVPV
596
ALAEG
601
LDIKL
606
NTAVR
611
QVRYT
616
ASGCE
621
VIAVN
626
TRSTS
631
QTFIY
636
KCDAV
641
LCTLP
646
LGVLK
651
QQPPA
656
VQFVP
661
PLPEW
666
KTSAV
671
QRMGF
676
GNLNK
681
VVLCF
686
DRVFW
691
DPSVN
696
LFGHV
701
GSTTA
706
SRGEL
711
FLFWN
716
LYKAP
721
ILLAL
726
VAGEA
731
AGIME
736
NISDD
741
VIVGR
746
CLAIL
751
KGIFG
756
SSAVP
761
QPKET
766
VVSRW
771
RADPW
776
ARGSY
781
SYVAA
786
GSSGN
791
DYDLM
796
AQPIT
801
PGPSI
806
PGAPQ
811
PIPRL
816
FFAGE
821
HTIRN
826
YPATV
831
HGALL
836
SGLRE
841
AGRIA
846
DQFLG
851
AMYTL
856
PRQAT
861
PGVPA
866
QQSPS
871
M
876
Mutation Information
DNA mutation:
None
Peptide Range:
784 ~ 808
Mut AA position:
796 (13 in Wild Type peptide)
Alignment
Wild Type:
"SYSYVAAGSSGNDYDLMAQPITPGP
||||||||||||.||||||||||||
Mutant:
SYSYVAAGSSGNNYDLMAQPITPGP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KDM1A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay