Immunogenicity 8693
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
FOXP3
Transcript ID
NM_001114377
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (396 aa)
MPNPR
1
PGKPS
6
APSLA
11
LGPSP
16
GASPS
21
WRAAP
26
KASDL
31
LGARG
36
PGGTF
41
QGRDL
46
RGGAH
51
ASSSS
56
LNPMP
61
PSQLQ
66
LSTVD
71
AHART
76
PVLQV
81
HPLES
86
PAMIS
91
LTPPT
96
TATGV
101
FSLKA
106
RPGLP
111
PGINV
116
ASLEW
121
VSREP
126
ALLCT
131
FPNPS
136
APRKD
141
STLSA
146
VPQSS
151
YPLLA
156
NGVCK
161
WPGCE
166
KVFEE
171
PEDFL
176
KHCQA
181
DHLLD
186
EKGRA
191
QCLLQ
196
REMVQ
201
SLEQQ
206
LVLEK
211
EKLSA
216
MQAHL
221
AGKMA
226
LTKAS
231
SVASS
236
DKGSC
241
CIVAA
246
GSQGP
251
VVPAW
256
SGPRE
261
APDSL
266
FAVRR
271
HLWGS
276
HGNST
281
FPEFL
286
HNMDY
291
FKFHN
296
MRPPF
301
TYATL
306
IRWAI
311
LEAPE
316
KQRTL
321
NEIYH
326
WFTRM
331
FAFFR
336
NHPAT
341
WKNAI
346
RHNLS
351
LHKCF
356
VRVES
361
EKGAV
366
WTVDE
371
LEFRK
376
KRSQR
381
PSRCS
386
NPTPG
391
P
396
Mutation Information
DNA mutation:
None
Peptide Range:
88 ~ 112
Mut AA position:
100 (13 in Wild Type peptide)
Alignment
Wild Type:
"LESPAMISLTPPTTATGVFSLKARP
||||||||||||.||||||||||||
Mutant:
LESPAMISLTPPPTATGVFSLKARP"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) FOXP3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay