Immunogenicity 87
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
NRXN1
Transcript ID
uc021vhk.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1523 aa)
MGTAL
1
LQRGG
6
CFLLC
11
LSLLL
16
LGCWA
21
ELGSG
26
LEFPG
31
AEGQW
36
TRFPK
41
WNACC
46
ESEMS
51
FQLKT
56
RSARG
61
LVLYF
66
DDEGF
71
CDFLE
76
LILTR
81
GGRLQ
86
LSFSI
91
FCAEP
96
ATLLA
101
DTPVN
106
DGAWH
111
SVRIR
116
RQFRN
121
TTLFI
126
DQVEA
131
KWVEV
136
KSKRR
141
DMTVF
146
SGLFV
151
GGLPP
156
ELRAA
161
ALKLT
166
LASVR
171
EREPF
176
KGWIR
181
DVRVN
186
SSQVL
191
PVDSG
196
EVKLD
201
DEPPN
206
SGGGS
211
PCEAG
216
EEGEG
221
GVCLN
226
GGVCS
231
VVDDQ
236
AVCDC
241
SRTGF
246
RGKDC
251
SQEDN
256
NVEGL
261
AHLMM
266
GDQGK
271
SKGKE
276
EYIAT
281
FKGSE
286
YFCYD
291
LSQNP
296
IQSSS
301
DEITL
306
SFKTL
311
QRNGL
316
MLHTG
321
KSADY
326
VNLAL
331
KNGAV
336
SLVIN
341
LGSGA
346
FEALV
351
EPVNG
356
KFNDN
361
AWHDV
366
KVTRN
371
LRQHS
376
GIGHA
381
MVNKL
386
HCSVT
391
ISVDG
396
ILTTT
401
GYTQE
406
DYTML
411
GSDDF
416
FYVGG
421
SPSTA
426
DLPGS
431
PVSNN
436
FMGCL
441
KEVVY
446
KNNDV
451
RLELS
456
RLAKQ
461
GDPKM
466
KIHGV
471
VAFKC
476
ENVAT
481
LDPIT
486
FETPE
491
SFISL
496
PKWNA
501
KKTGS
506
ISFDF
511
RTTEP
516
NGLIL
521
FSHGK
526
PRHQK
531
DAKHP
536
QMIKV
541
DFFAI
546
EMLDG
551
HLYLL
556
LDMGS
561
GTIKI
566
KALLK
571
KVNDG
576
EWYHV
581
DFQRD
586
GRSGT
591
ISVNT
596
LRTPY
601
TAPGE
606
SEILD
611
LDDEL
616
YLGGL
621
PENKA
626
GLVFP
631
TEVWT
636
ALLNY
641
GYVGC
646
IRDLF
651
IDGQS
656
KDIRQ
661
MAEVQ
666
STAGV
671
KPSCS
676
KETAK
681
PCLSN
686
PCKNN
691
GMCRD
696
GWNRY
701
VCDCS
706
GTGYL
711
GRSCE
716
REATV
721
LSYDG
726
SMFMK
731
IQLPV
736
VMHTE
741
AEDVS
746
LRFRS
751
QRAYG
756
ILMAT
761
TSRDS
766
ADTLR
771
LELDA
776
GRVKL
781
TVNLD
786
CIRIN
791
CNSSK
796
GPETL
801
FAGYN
806
LNDNE
811
WHTVR
816
VVRRG
821
KSLKL
826
TVDDQ
831
QAMTG
836
QMAGD
841
HTRLE
846
FHNIE
851
TGIIT
856
ERRYL
861
SSVPS
866
NFIGH
871
LQSLT
876
FNGMA
881
YIDLC
886
KNGDI
891
DYCEL
896
NARFG
901
FRNII
906
ADPVT
911
FKTKS
916
SYVAL
921
ATLQA
926
YTSMH
931
LFFQF
936
KTTSL
941
DGLIL
946
YNSGD
951
GNDFI
956
VVELV
961
KGYLH
966
YVFDL
971
GNGAN
976
LIKGS
981
SNKPL
986
NDNQW
991
HNVMI
996
SRDTS
1001
NLHTV
1006
KIDTK
1011
ITTQI
1016
TAGAR
1021
NLDLK
1026
SDLYI
1031
GGVAK
1036
ETYKS
1041
LPKLV
1046
HAKEG
1051
FQGCL
1056
ASVDL
1061
NGRLP
1066
DLISD
1071
ALFCN
1076
GQIER
1081
GCEVA
1086
LMKAD
1091
LQGPS
1096
TTCQE
1101
DSCSN
1106
QGVCL
1111
QQWDG
1116
FSCDC
1121
SMTSF
1126
SGPLC
1131
NDPGT
1136
TYIFS
1141
KGGGQ
1146
ITYKW
1151
PPNDR
1156
PSTRA
1161
DRLAI
1166
GFSTV
1171
QKEAV
1176
LVRVD
1181
SSSGL
1186
GDYLE
1191
LHIHQ
1196
GKIGV
1201
KFNVG
1206
TDDIA
1211
IEESN
1216
AIIND
1221
GKYHV
1226
VRFTR
1231
SGGNA
1236
TLQVD
1241
SWPVI
1246
ERYPA
1251
GNNDN
1256
ERLAI
1261
ARQRI
1266
PYRLG
1271
RVVDE
1276
WLLDK
1281
GRQLT
1286
IFNSQ
1291
ATIII
1296
GGKEQ
1301
GQPFQ
1306
GQLSG
1311
LYYNG
1316
LKVLN
1321
MAAEN
1326
DANIA
1331
IVGNV
1336
RLVGE
1341
VPSSM
1346
TTEST
1351
ATAMQ
1356
SEMST
1361
SIMET
1366
TTTLA
1371
TSTAR
1376
RGKPP
1381
TKEPI
1386
SQTTD
1391
DILVA
1396
SAECP
1401
SDDED
1406
IDPCE
1411
PSSGG
1416
LANPT
1421
RAGGR
1426
EPYPG
1431
SAEVI
1436
RESSS
1441
TTGMV
1446
VGIVA
1451
AAALC
1456
ILILL
1461
YAMYK
1466
YRNRD
1471
EGSYH
1476
VDESR
1481
NYISN
1486
SAQSN
1491
GAVVK
1496
EKQPS
1501
SAKSS
1506
NKNKK
1511
NKDKE
1516
YYV
1521
Mutation Information
DNA mutation:
c.T385A
Peptide Range:
117 ~ 141
Mut AA position:
129 (13 in Wild Type peptide)
Alignment
Wild Type:
"VRIRRQFRNTTLFIDQVEAKWVEVK
||||||||||||.||||||||||||
Mutant:
VRIRRQFRNTTLIIDQVEAKWVEVK"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) NRXN1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VRIRRQFRNTTLIIDQVEAKWVEVK
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT