Immunogenicity 8706

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MACC1
Transcript ID
NM_182762
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (852 aa)
MLITE
1
RKHFR
6
SGRIA
11
QSMSE
16
ANLID
21
MEAGK
26
LSKSC
31
NITEC
36
QDPDL
41
LHNWP
46
DAFTL
51
RGNNA
56
SKVAN
61
PFWNQ
66
LSASN
71
PFLDD
76
ITQLR
81
NNRKR
86
NNISI
91
LKEDP
96
FLFCR
101
EIENG
106
NSFDS
111
SGDEL
116
DVHQL
121
LRQTS
126
SRNSG
131
RSKSV
136
SELLD
141
ILDDT
146
AHAHQ
151
SIHNS
156
DQILL
161
HDLEW
166
LKNDR
171
EAYKM
176
AWLSQ
181
RQLAR
186
SCLDL
191
NTISQ
196
SPGWA
201
QTQLA
206
EVTIA
211
CKVNH
216
QGGSV
221
QLPES
226
DITVH
231
VPQGH
236
VAVGE
241
FQEVS
246
LRAFL
251
DPPHM
256
LNHDL
261
SCTVS
266
PLLEI
271
MLGNL
276
NTMEA
281
LLLEM
286
KIGAE
291
VRKDP
296
FSQVM
301
TEMVC
306
LHSLG
311
KEGPF
316
KVLSN
321
CYIYK
326
DTIQV
331
KLIDL
336
SQVMY
341
LVVAA
346
QAKAL
351
PSPAA
356
TIWDY
361
IHKTT
366
SIGIY
371
GPKYI
376
HPSFT
381
VVLTV
386
CGHNY
391
MPGQL
396
TISDI
401
KKGGK
406
NISPV
411
VFQLW
416
GKQSF
421
LLDKP
426
QDLSI
431
SIFSC
436
DPDFE
441
VKTEG
446
ERKEI
451
KQKQL
456
EAGEV
461
VHQQF
466
LFSLV
471
EHREM
476
HLFDF
481
CVQVE
486
PPNGE
491
PVAQF
496
SITTP
501
DPTPN
506
LKRLS
511
NLPGY
516
LQKKE
521
EIKSA
526
PLSPK
531
ILVKY
536
PTFQD
541
KTLNF
546
SNYGV
551
TLKAV
556
LRQSK
561
IDYFL
566
EYFKG
571
DTIAL
576
LGEGK
581
VKAIG
586
QSKVK
591
EWYVG
596
VLRGK
601
IGLVH
606
CKNVK
611
VISKE
616
QVMFM
621
SDSVF
626
TTRNL
631
LEQIV
636
LPLKK
641
LTYIY
646
SVVLT
651
LVSEK
656
VYDWK
661
VLADV
666
LGYSH
671
LSLED
676
FDQIQ
681
ADKES
686
EKVSY
691
VIKKL
696
KEDCH
701
TERNT
706
RKFLY
711
ELIVA
716
LLKMD
721
CQELV
726
ARLIQ
731
EAAVL
736
TSAVK
741
LGKGW
746
RELAE
751
KLVRL
756
TKQQM
761
EAYEI
766
PHRGN
771
TGDVA
776
VEMMW
781
KPAYD
786
FLYTW
791
SAHYG
796
NNYRD
801
VLQDL
806
QSALD
811
RMKNP
816
VTKHW
821
RELTG
826
VLILV
831
NSLEV
836
LRVTA
841
FSTSE
846
EV
851
Mutation Information
DNA mutation:
None
Peptide Range:
318 ~ 342
Mut AA position:
330 (13 in Wild Type peptide)
Alignment
Wild Type:
"GPFKVLSNCYIYKDTIQVKLIDLSQ
||||||||||||.||||||||||||
Mutant:
GPFKVLSNCYIYQDTIQVKLIDLSQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MACC1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay