Immunogenicity 8716

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GRIK4
Transcript ID
NM_014619
HLA INFO
A*30:02
TCR INFO

No TCR info found!

T cell Tumor cell A*30:02
sequence
Full length protein sequence (956 aa)
MPRVS
1
APLVL
6
LPAWL
11
VMVAC
16
SPHSL
21
RIAAI
26
LDDPM
31
ECSRG
36
ERLSI
41
TLAKN
46
RINRA
51
PERLG
56
KAKVE
61
VDIFE
66
LLRDS
71
EYETA
76
ETMCQ
81
ILPKG
86
VVAVL
91
GPSSS
96
PASSS
101
IISNI
106
CGEKE
111
VPHFK
116
VAPEE
121
FVKFQ
126
FQRFT
131
TLNLH
136
PSNTD
141
ISVAV
146
AGILN
151
FFNCT
156
TACLI
161
CAKAE
166
CLLNL
171
EKLLR
176
QFLIS
181
KDTLS
186
VRMLD
191
DTRDP
196
TPLLK
201
EIRDD
206
KTATI
211
IIHAN
216
ASMSH
221
TILLK
226
AAELG
231
MVSAY
236
YTYIF
241
TNLEF
246
SLQRM
251
DSLVD
256
DRVNI
261
LGFSI
266
FNQSH
271
AFFQE
276
FAQSL
281
NQSWQ
286
ENCDH
291
VPFTG
296
PALSS
301
ALLFD
306
AVYAV
311
VTAVQ
316
ELNRS
321
QEIGV
326
KPLSC
331
GSAQI
336
WQHGT
341
SLMNY
346
LRMVE
351
LEGLT
356
GHIEF
361
NSKGQ
366
RSNYA
371
LKILQ
376
FTRNG
381
FRQIG
386
QWHVA
391
EGLSM
396
DSHLY
401
ASNIS
406
DTLFN
411
TTLVV
416
TTILE
421
NPYLM
426
LKGNH
431
QEMEG
436
NDRYE
441
GFCVD
446
MLKEL
451
AEILR
456
FNYKI
461
RLVGD
466
GVYGV
471
PEANG
476
TWTGM
481
VGELI
486
ARKAD
491
LAVAG
496
LTITA
501
EREKV
506
IDFSK
511
PFMTL
516
GISIL
521
YRVHM
526
GRKPG
531
YFSFL
536
DPFSP
541
GVWLF
546
MLLAY
551
LAVSC
556
VLFLV
561
ARLTP
566
YEWYS
571
PHPCA
576
QGRCN
581
LLVNQ
586
YSLGN
591
SLWFP
596
VGGFM
601
QQGST
606
IAPRA
611
LSTRC
616
VSGVW
621
WAFTL
626
IIISS
631
YTANL
636
AAFLT
641
VQRMD
646
VPIES
651
VDDLA
656
DQTAI
661
EYGTI
666
HGGSS
671
MTFFQ
676
NSRYQ
681
TYQRM
686
WNYMY
691
SKQPS
696
VFVKS
701
TEEGI
706
ARVLN
711
SNYAF
716
LLEST
721
MNEYY
726
RQRNC
731
NLTQI
736
GGLLD
741
TKGYG
746
IGMPV
751
GSVFR
756
DEFDL
761
AILQL
766
QENNR
771
LEILK
776
RKWWE
781
GGKCP
786
KEEDH
791
RAKGL
796
GMENI
801
GGIFV
806
VLICG
811
LIVAI
816
FMAML
821
EFLWT
826
LRHSE
831
ATEVS
836
VCQEM
841
VTELR
846
SIILC
851
QDSIH
856
PRRRR
861
AAVPP
866
PRPPI
871
PEERR
876
PRGTA
881
TLSNG
886
KLCGA
891
GEPDQ
896
LAQRL
901
AQEAA
906
LVARG
911
CTHIR
916
VCPEC
921
RRFQG
926
LRARP
931
SPARS
936
EESLE
941
WEKTT
946
NSSEP
951
E
956
Mutation Information
DNA mutation:
None
Peptide Range:
848 ~ 872
Mut AA position:
860 (13 in Wild Type peptide)
Alignment
Wild Type:
"ELRSIILCQDSIHPRRRRAAVPPPR
||||||||||||.||||||||||||
Mutant:
ELRSIILCQDSIPPRRRRAAVPPPR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GRIK4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay