Immunogenicity 873

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SHROOM4
Transcript ID
ENST00000460112
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (1377 aa)
MHFPS
1
EAFSL
6
SWHSG
11
CNTSD
16
VCVQW
21
CPLSR
26
HCSTE
31
KSSSI
36
GSMES
41
LEQPG
46
QATYE
51
SHLLP
56
IDQNM
61
YPNQR
66
DSAYS
71
SFSAS
76
SNASD
81
CALSL
86
RPEEP
91
ASTDC
96
IMQGP
101
GPTKA
106
PSGRP
111
NVAET
116
SGGSR
121
RTNGG
126
HLTPS
131
SQMSS
136
RPQEG
141
YQSGP
146
AKAVR
151
GPPQP
156
PVRRD
161
SLQAS
166
RAQLL
171
NGEQR
176
RASEP
181
VVPLP
186
QKEKL
191
SLEPV
196
LPARN
201
PNRFC
206
CLSGH
211
DQVTS
216
EGHQN
221
CEFSQ
226
PPESS
231
QQGSE
236
HLLMQ
241
ASTKA
246
VGSPK
251
ACDRA
256
SSVDS
261
NPLNE
266
ASAEL
271
AKASF
276
GRPPH
281
LIGPT
286
GHRHS
291
APEQL
296
LASHL
301
QHVHL
306
DTRGS
311
KGMEL
316
PPVQD
321
GHQWT
326
LSPLH
331
SSHKG
336
KKSPC
341
PPTGG
346
THDQS
351
SKERK
356
TRQVD
361
DRSLV
366
LGHQS
371
QSSPP
376
HGEAD
381
GHPSE
386
KGFLD
391
PNRTS
396
RAASE
401
LANQQ
406
PSASG
411
SLVQQ
416
ATDCS
421
STTKA
426
ASGTE
431
AGEEG
436
DSEPK
441
ECSRM
446
GGRRS
451
GGTRG
456
RSIQN
461
RRKSE
466
RFATN
471
LRNEI
476
QRRKA
481
QLQKS
486
KGPLS
491
QLCDT
496
KEPVE
501
ETQEP
506
PESPP
511
LTASN
516
TSLLS
521
SCKKP
526
PSPRD
531
KLFNK
536
SMMLR
541
ARSSE
546
CLSQA
551
PESHE
556
SRTGL
561
EGRIS
566
PGQRP
571
GQSSL
576
GLNTW
581
WKAPD
586
PSSSD
591
PEKAH
596
AHCGV
601
RGGHW
606
RWSPE
611
HNSQP
616
LVAAA
621
MEGPS
626
NPGDN
631
KELKA
636
STAQA
641
GEDAI
646
LLPFA
651
DRRKF
656
FEESS
661
KSLST
666
SHLPG
671
LTTHS
676
NKTFT
681
QRPKP
686
IDQNF
691
QPMSS
696
SCREL
701
RRHPM
706
DQSYH
711
SADQP
716
YHATD
721
QSYHS
726
MSPLQ
731
SETPT
736
YSECF
741
ASKGL
746
ENSMC
751
CKPLH
756
CGDFD
761
YHRTC
766
SYSCS
771
VQGAL
776
VHDPC
781
IYCSG
786
EICPA
791
LLKRN
796
MMPNC
801
YNCRC
806
HHHQC
811
IRCSV
816
CYHNP
821
QHSAL
826
EDSSL
831
APGNT
836
WKPRK
841
LTVQE
846
FPGDK
851
WNPIT
856
GNRKT
861
SQSGR
866
EMAHS
871
KTSFS
876
WATPF
881
HPCLE
886
NPALD
891
LSSYR
896
AISSL
901
DLLGD
906
FKHAL
911
KKSEE
916
TSVYE
921
EGSSL
926
ASMPH
931
PLRSR
936
AFSES
941
HISLA
946
PQSTR
951
AWGQH
956
RRELF
961
SKGDE
966
TQSDL
971
LGARK
976
KAFPP
981
PRPPP
986
PNWEK
991
YRLFR
996
AAQQQ
1001
KQQQQ
1006
QQKQQ
1011
EEEEE
1016
EEEEE
1021
EEEEE
1026
EEEEE
1031
AEEEE
1036
EELPP
1041
QYFSS
1046
ETSGS
1051
CALNP
1056
EEVLE
1061
QPQPL
1066
SFGHL
1071
EGSRQ
1076
GSQSV
1081
PAEQE
1086
SFALH
1091
SSDFL
1096
PPIRG
1101
HLGSQ
1106
PEQAQ
1111
PPCYY
1116
GIGGL
1121
WRTSG
1126
QEATE
1131
SAKQE
1136
FQHFS
1141
PPSGA
1146
PGIPT
1151
SYSAY
1156
YNISV
1161
AKAEL
1166
LNKLK
1171
DQPEM
1176
AEIGL
1181
GEEEV
1186
DHELA
1191
QKKIQ
1196
LIESI
1201
SRKLS
1206
VLREA
1211
QRGLL
1216
EDINA
1221
NSALG
1226
EEVEA
1231
NLKAV
1236
CKSNE
1241
FEKYH
1246
LFVGD
1251
LDKVV
1256
NLLLS
1261
LSGRL
1266
ARVEN
1271
ALNSI
1276
DSEAN
1281
QEKLV
1286
LIEKK
1291
QQLTG
1296
QLADA
1301
KELKE
1306
HVDRR
1311
EKLVF
1316
GMVSR
1321
YLPQD
1326
QLQDY
1331
QHFVK
1336
MKSAL
1341
IIEQR
1346
ELEEK
1351
IKLGE
1356
EQLKC
1361
LRESL
1366
LLGPS
1371
NF
1376
Mutation Information
DNA mutation:
None
Peptide Range:
1264 ~ 1288
Mut AA position:
1276 (13 in Wild Type peptide)
Alignment
Wild Type:
"LSLSGRLARVENALNSIDSEANQEK
||||||||||||.||||||||||||
Mutant:
LSLSGRLARVENDLNSIDSEANQEK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SHROOM4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay