Immunogenicity 8740

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
MACROD1
Transcript ID
NM_014067
HLA INFO
B*27:03
TCR INFO

No TCR info found!

T cell Tumor cell B*27:03
sequence
Full length protein sequence (325 aa)
MSLQS
1
RLSGR
6
LAQLR
11
AAGQL
16
LVPPR
21
PRPGH
26
LAGAT
31
RTRSS
36
TCGPP
41
AFLGV
46
FGRRA
51
RTSAG
56
VGAWG
61
AAAVG
66
RTAGV
71
RTWAP
76
LAMAA
81
KVDLS
86
TSTDW
91
KEAKS
96
FLKGL
101
SDKQR
106
EEHYF
111
CKDFV
116
RLKKI
121
PTWKE
126
MAKGV
131
AVKVE
136
EPRYK
141
KDKQL
146
NEKIS
151
LLRSD
156
ITKLE
161
VDAIV
166
NAANS
171
SLLGG
176
GGVDG
181
CIHRA
186
AGPLL
191
TDECR
196
TLQSC
201
KTGKA
206
KITGG
211
YRLPA
216
KYVIH
221
TVGPI
226
AYGEP
231
SASQA
236
AELRS
241
CYLSS
246
LDLLL
251
EHRLR
256
SVAFP
261
CISTG
266
VFGYP
271
CEAAA
276
EIVLA
281
TLREW
286
LEQHK
291
DKVDR
296
LIICV
301
FLEKD
306
EDIYR
311
SRLPH
316
YFPVA
321
Mutation Information
DNA mutation:
None
Peptide Range:
122 ~ 146
Mut AA position:
134 (13 in Wild Type peptide)
Alignment
Wild Type:
"LKKIPTWKEMAKGVAVKVEEPRYKK
||||||||||||.||||||||||||
Mutant:
LKKIPTWKEMAKWVAVKVEEPRYKK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MACROD1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay