Immunogenicity 8837

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
MAGEC1
Transcript ID
NM_005462
HLA INFO
C*03:04
TCR INFO

No TCR info found!

T cell Tumor cell C*03:04
sequence
Full length protein sequence (1142 aa)
MGDKD
1
MPTAG
6
MPSLL
11
QSSSE
16
SPQSC
21
PEGED
26
SQSPL
31
QIPQS
36
SPESD
41
DTLYP
46
LQSPQ
51
SRSEG
56
EDSSD
61
PLQRP
66
PEGKD
71
SQSPL
76
QIPQS
81
SPEGD
86
DTQSP
91
LQNSQ
96
SSPEG
101
KDSLS
106
PLEIS
111
QSPPE
116
GEDVQ
121
SPLQN
126
PASSF
131
FSSAL
136
LSIFQ
141
SSPES
146
TQSPF
151
EGFPQ
156
SVLQI
161
PVSAA
166
SSSTL
171
VSIFQ
176
SSPES
181
TQSPF
186
EGFPQ
191
SPLQI
196
PVSRS
201
FSSTL
206
LSIFQ
211
SSPER
216
TQSTF
221
EGFAQ
226
SPLQI
231
PVSPS
236
SSSTL
241
LSLFQ
246
SFSER
251
TQSTF
256
EGFAQ
261
SSLQI
266
PVSPS
271
FSSTL
276
VSLFQ
281
SSPER
286
TQSTF
291
EGFPQ
296
SPLQI
301
PVSSS
306
SSSTL
311
LSLFQ
316
SSPER
321
THSTF
326
EGFPQ
331
SLLQI
336
PMTSS
341
FSSTL
346
LSIFQ
351
SSPES
356
AQSTF
361
EGFPQ
366
SPLQI
371
PGSPS
376
FSSTL
381
LSLFQ
386
SSPER
391
THSTF
396
EGFPQ
401
SPLQI
406
PMTSS
411
FSSTL
416
LSILQ
421
SSPES
426
AQSAF
431
EGFPQ
436
SPLQI
441
PVSSS
446
FSYTL
451
LSLFQ
456
SSPER
461
THSTF
466
EGFPQ
471
SPLQI
476
PVSSS
481
SSSST
486
LLSLF
491
QSSPE
496
CTQST
501
FEGFP
506
QSPLQ
511
IPQSP
516
PEGEN
521
THSPL
526
QIVPS
531
LPEWE
536
DSLSP
541
HYFPQ
546
SPPQG
551
EDSLS
556
PHYFP
561
QSPPQ
566
GEDSL
571
SPHYF
576
PQSPQ
581
GEDSL
586
SPHYF
591
PQSPP
596
QGEDS
601
MSPLY
606
FPQSP
611
LQGEE
616
FQSSL
621
QSPVS
626
ICSSS
631
TPSSL
636
PQSFP
641
ESSQS
646
PPEGP
651
VQSPL
656
HSPQS
661
PPEGM
666
HSQSP
671
LQSPE
676
SAPEG
681
EDSLS
686
PLQIP
691
QSPLE
696
GEDSL
701
SSLHF
706
PQSPP
711
EWEDS
716
LSPLH
721
FPQFP
726
PQGED
731
FQSSL
736
QSPVS
741
ICSSS
746
TSLSL
751
PQSFP
756
ESPQS
761
PPEGP
766
AQSPL
771
QRPVS
776
SFFSY
781
TLASL
786
LQSSH
791
ESPQS
796
PPEGP
801
AQSPL
806
QSPVS
811
SFPSS
816
TSSSL
821
SQSSP
826
VSSFP
831
SSTSS
836
SLSKS
841
SPESP
846
LQSPV
851
ISFSS
856
STSLS
861
PFSEE
866
SSSPV
871
DEYTS
876
SSDTL
881
LESDS
886
LTDSE
891
SLIES
896
EPLFT
901
YTLDE
906
KVDEL
911
ARFLL
916
LKYQV
921
KQPIT
926
KAEML
931
TNVIS
936
RYTGY
941
FPVIF
946
RKARE
951
FIEIL
956
FGISL
961
REVDP
966
DDSYV
971
FVNTL
976
DLTSE
981
GCLSD
986
EQGMS
991
QNRLL
996
ILILS
1001
IIFIK
1006
GTYAS
1011
EEVIW
1016
DVLSG
1021
IGVRA
1026
GREHF
1031
AFGEP
1036
RELLT
1041
KVWVQ
1046
EHYLE
1051
YREVP
1056
NSSPP
1061
RYEFL
1066
WGPRA
1071
HSEVI
1076
KRKVV
1081
EFLAM
1086
LKNTV
1091
PITFP
1096
SSYKD
1101
ALKDV
1106
EERAQ
1111
AIIDT
1116
TDDST
1121
ATESA
1126
SSSVM
1131
SPSFS
1136
SE
1141
Mutation Information
DNA mutation:
None
Peptide Range:
283 ~ 307
Mut AA position:
295 (13 in Wild Type peptide)
Alignment
Wild Type:
"LFQSSPERTQSTFEGFPQSPLQIPV
||||||||||||.||||||||||||
Mutant:
LFQSSPERTQSTSEGFPQSPLQIPV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MAGEC1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay