Immunogenicity 89
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
MARK1
Transcript ID
uc010pun.2
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (781 aa)
MSART
1
PLPTV
6
NERDT
11
ENHTS
16
VDGYT
21
EPHIQ
26
PTKSS
31
SRQNI
36
PRCRN
41
SITSA
46
TDEQP
51
HIGNY
56
RLQKT
61
IGKGN
66
FAKVK
71
LARHV
76
LTGRE
81
VAVKI
86
IDKTQ
91
LNPTS
96
LQKLF
101
REVRI
106
MKILN
111
HPNIV
116
KLFEV
121
IETEK
126
TLYLV
131
MEYAS
136
GGEVF
141
DYLVA
146
HGRMK
151
EKEAR
156
AKFRQ
161
IVSAV
166
QYCHQ
171
KYIVH
176
RDLKA
181
ENLLL
186
DGDMN
191
IKIAD
196
FGFSN
201
EFTVG
206
NKLDT
211
FCGSP
216
PYAAP
221
ELFQG
226
KKYDG
231
PEVDV
236
WSLGV
241
ILYTL
246
VSGSL
251
PFDGQ
256
NLKEL
261
RERVL
266
RGKYR
271
IPFYM
276
STDCE
281
NLLKK
286
LLVLN
291
PIKRG
296
SLEQI
301
MKDRW
306
MNVGH
311
EEEEL
316
KPYTE
321
PDPDF
326
NDTKR
331
IDIMV
336
TMGFA
341
RDEIN
346
DALIN
351
QKYDE
356
VMATY
361
ILLGR
366
KPPEF
371
EGGES
376
LSSGN
381
LCQRS
386
RPSSD
391
LNNST
396
LQSPA
401
HLKVQ
406
RSISA
411
NQKQR
416
RFSDH
421
AGPSI
426
PPAVS
431
YTKRP
436
QANSV
441
ESEQK
446
EEWDK
451
DVARK
456
LGSTT
461
VGSKS
466
EMTAS
471
PLVGP
476
ERKKS
481
STIPS
486
NNVYS
491
GGSMA
496
RRNTY
501
VCERT
506
TDRYV
511
ALQNG
516
KDSSL
521
TEMSV
526
SSISS
531
AGSSV
536
ASAVP
541
SARPR
546
HQKSM
551
STSGH
556
PIKVT
561
LPTIK
566
DGSEA
571
YRPGS
576
TTQRV
581
PAASP
586
SAHSI
591
STATP
596
DRTRF
601
PRGSS
606
SRSTF
611
HGEQL
616
RERRS
621
VAYNG
626
PPASP
631
SHETG
636
AFAHA
641
RRGTS
646
TGIIS
651
KITSK
656
FVRRS
661
TSGEP
666
KERDK
671
EEGKD
676
SKPRS
681
LRFTW
686
SMKTT
691
SSMDP
696
NDMMR
701
EIRKV
706
LDANN
711
CDYEQ
716
KERFL
721
LFCVH
726
GDARQ
731
DSLVQ
736
WEMEV
741
CKLPR
746
LSLNG
751
VRFKR
756
ISGTS
761
IAFKN
766
IASKI
771
ANELK
776
L
781
Mutation Information
DNA mutation:
c.A167T
Peptide Range:
44 ~ 68
Mut AA position:
56 (13 in Wild Type peptide)
Alignment
Wild Type:
"RNSITSATDEQPHIGNYRLQKTIGK
||||||||||||.||||||||||||
Mutant:
RNSITSATDEQPLIGNYRLQKTIGK"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) MARK1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
RNSITSATDEQPLIGNYRLQKTIGK
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT