Immunogenicity 895
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
NBEA
Transcript ID
ENST00000540320
HLA INFO
B*44:03
TCR INFO
No TCR info found!
Full length protein sequence (2946 aa)
MASEK
1
PGPGP
6
GLEPQ
11
PVGLI
16
AVGAA
21
GGGGG
26
GSGGG
31
GTGGS
36
GMGEL
41
RGASG
46
SGSVM
51
LPAGM
56
INPSV
61
PIRNI
66
RMKFA
71
VLIGL
76
IQVGE
81
VSNRD
86
IVETV
91
LNLLV
96
GGEFD
101
LEMNF
106
IIQDA
111
ESITC
116
MTELL
121
EHCDV
126
TCQAE
131
IWSMF
136
TAILR
141
KSVRN
146
LQTST
151
EVGLI
156
EQVLL
161
KMSAV
166
DDMIA
171
DLLVD
176
MLGVL
181
ASYSI
186
TVKEL
191
KLLFS
196
MLRGE
201
SGIWP
206
RHAVK
211
LLSVL
216
NQMPQ
221
RHGPD
226
TFFNF
231
PGCSA
236
AAIAL
241
PPIAK
246
WPYQN
251
GFTLN
256
TWFRM
261
DPLNN
266
INVDK
271
DKPYL
276
YCFRT
281
SKGVG
286
YSAHF
291
VGNCL
296
IVTSL
301
KSKGK
306
GFQHC
311
VKYDF
316
QPRKW
321
YMISI
326
VHIYN
331
RWRNS
336
EIRCY
341
VNGQL
346
VSYGD
351
MAWHV
356
NTNDS
361
YDKCF
366
LGSSE
371
TADAN
376
RVFCG
381
QLGAV
386
YVFSE
391
ALNPA
396
QIFAI
401
HQLGP
406
GYKST
411
FKFKS
416
ESDIH
421
LAEHH
426
KQVLY
431
DGKLA
436
SSIAF
441
TYNAK
446
ATDAQ
451
LCLES
456
SPKEN
461
ASIFV
466
HSPHA
471
LMLQD
476
VKAIV
481
THSIH
486
SAIHS
491
IGGIQ
496
VLFPL
501
FAQLD
506
NRQLN
511
DSQVE
516
TTVCA
521
TLLAF
526
LVELL
531
KSSVA
536
MQEQM
541
LGGKG
546
FLVIG
551
YLLEK
556
SSRVH
561
ITRAV
566
LEQFL
571
SFAKY
576
LDGLS
581
HGAPL
586
LKQLC
591
DHILF
596
NPAIW
601
IHTPA
606
KVQLS
611
LYTYL
616
SAEFI
621
GTATI
626
YTTIR
631
RVGTV
636
LQLMH
641
TLKYY
646
YWVIN
651
PADSS
656
GITPK
661
GLDGP
666
RPSQK
671
EIISL
676
RAFML
681
LFLKQ
686
LILKD
691
RGVKE
696
DELQS
701
ILNYL
706
LTMHE
711
DENIH
716
DVLQL
721
LVALM
726
SEHPA
731
SMIPA
736
FDQRN
741
GIRVI
746
YKLLA
751
SKSES
756
IWVQA
761
LKVLG
766
YFLKH
771
LGHKR
776
KVEIM
781
HTHSL
786
FTLLG
791
ERLML
796
HTNTV
801
TVTTY
806
NTLYE
811
ILTEQ
816
VCTQV
821
VHKPH
826
PEPDS
831
TVKIQ
836
NPMIL
841
KVVAT
846
LLKNS
851
TPSAE
856
LMEVR
861
RLFLS
866
DMIKL
871
FSNSR
876
ENRRC
881
LLQCS
886
VWQDW
891
MFSLG
896
YINPK
901
NSEEQ
906
KITEM
911
VYNIF
916
RILLY
921
HAIKY
926
EWGGW
931
RVWVD
936
TLSIA
941
HSKVT
946
YEAHK
951
EYLAK
956
MYEEY
961
QRQEE
966
ENIKK
971
GKKGN
976
VSTIS
981
GLSSQ
986
TTGAK
991
GGMEI
996
REIED
1001
LSQSQ
1006
SPESE
1011
TDYPV
1016
STDTR
1021
DLLMS
1026
TKVSD
1031
DILGN
1036
SDRPG
1041
SGVHV
1046
EVHDL
1051
LVDIK
1056
AEKVE
1061
ATEVK
1066
LDDMD
1071
LSPET
1076
LVGGE
1081
NGALV
1086
EVESL
1091
LDNVY
1096
SAAVE
1101
KLQNN
1106
VHGSV
1111
GIIKK
1116
NEEKD
1121
NGPLI
1126
TLADE
1131
KEDLP
1136
NSSTS
1141
FLFDK
1146
IPKQE
1151
EKLLP
1156
ELSSN
1161
HIIPN
1166
IQDTQ
1171
VHLGV
1176
SDDLG
1181
LLAHM
1186
TGSVD
1191
LTCTS
1196
SIIEE
1201
KEFKI
1206
HTTSD
1211
GMSSI
1216
SERDL
1221
ASSTK
1226
GLEYA
1231
EMTAT
1236
TLETE
1241
SSSSK
1246
IVPNI
1251
DAGSI
1256
ISDTE
1261
RSDDG
1266
KESGK
1271
EIRKI
1276
QTTTT
1281
TQAVQ
1286
GRSIT
1291
QQDRD
1296
LRVDL
1301
GFRGM
1306
PMTEE
1311
QRRQF
1316
SPGPR
1321
TTMFR
1326
IPEFK
1331
WSPMH
1336
QRLLT
1341
DLLFA
1346
LETDV
1351
HVWRS
1356
HSTKS
1361
VMDFV
1366
NSNEN
1371
IIFVH
1376
NTIHL
1381
ISQMV
1386
DNIII
1391
ACGGI
1396
LPLLS
1401
AATSP
1406
TVSKT
1411
ELENI
1416
EVTQG
1421
MSAET
1426
AVTFL
1431
SRLMA
1436
MVDVL
1441
VFASS
1446
LNFSE
1451
IEAEK
1456
NMSSG
1461
GLMRQ
1466
CLRLV
1471
CCVAV
1476
RNCLE
1481
CRQRQ
1486
RDRGN
1491
KSSHG
1496
SSKPQ
1501
EVPQS
1506
VTATA
1511
ASKTP
1516
LENVP
1521
GNLSP
1526
IKDPD
1531
RLLQD
1536
VDINR
1541
LRAVV
1546
FRDVD
1551
DSKQA
1556
QFLAL
1561
AVVYF
1566
ISVLM
1571
VSKYR
1576
DILEP
1581
QRETT
1586
RTGSQ
1591
PGRNI
1596
RQEIN
1601
SPTST
1606
VVVIP
1611
SIPHP
1616
SLNHG
1621
FLAKL
1626
IPEQS
1631
FGHSF
1636
YKETP
1641
AAFPD
1646
TIKEK
1651
ETPTP
1656
GEDIQ
1661
VESSI
1666
PHTDS
1671
GIGEE
1676
QVASI
1681
LNGAE
1686
LETST
1691
GPDAM
1696
SELLS
1701
TLSSE
1706
VKKSQ
1711
ESLTE
1716
NPSET
1721
LKPAT
1726
SISSI
1731
SQTKG
1736
INVKE
1741
ILKSL
1746
VAAPV
1751
EIAEC
1756
GPEPI
1761
PYPDP
1766
ALKRE
1771
TQAIL
1776
PMQFH
1781
SFDRS
1786
VVVPV
1791
KKPPP
1796
GSLAV
1801
TTVGA
1806
TTAGS
1811
GLPTG
1816
STSNI
1821
FAATG
1826
ATPKS
1831
MINTT
1836
GAVDS
1841
GSSSS
1846
SSSSS
1851
FVNGA
1856
TSKNL
1861
PAVQT
1866
VAPMP
1871
EDSAE
1876
NMSIT
1881
AKLER
1886
ALEKV
1891
APLLR
1896
EIFVD
1901
FAPFL
1906
SRTLL
1911
GSHGQ
1916
ELLIE
1921
GLVCM
1926
KSSTS
1931
VVELV
1936
MLLCS
1941
QEWQN
1946
SIQKN
1951
AGLAF
1956
IELIN
1961
EGRLL
1966
CHAMK
1971
DHIVR
1976
VANEA
1981
EFILN
1986
RQRAE
1991
DVHKH
1996
AEFES
2001
QCAQY
2006
AADRR
2011
EEEKM
2016
CDHLI
2021
SAAKH
2026
RDHVT
2031
ANQLK
2036
QKILN
2041
ILTNK
2046
HGAWG
2051
AVSHS
2056
QLHDF
2061
WRLDY
2066
WEDDL
2071
RRRRR
2076
FVRNA
2081
FGSTH
2086
AEALL
2091
KAAIE
2096
YGTEE
2101
DVVKS
2106
KKTFR
2111
SQAIV
2116
NQNAE
2121
TELML
2126
EGDDD
2131
AVSLL
2136
QEKEI
2141
DNLAG
2146
PVVLS
2151
TPAQL
2156
IAPVV
2161
VAKGT
2166
LSITT
2171
TEIYF
2176
EVDED
2181
DSAFK
2186
KIDTK
2191
VLAYT
2196
EGLHG
2201
KWMFS
2206
EIRAV
2211
FSRRY
2216
LLQNT
2221
ALEVF
2226
MANRT
2231
SVMFN
2236
FPDQA
2241
TVKKV
2246
VYSLP
2251
RVGVG
2256
TSYGL
2261
PQARR
2266
ISLAT
2271
PRQLY
2276
KSSNM
2281
TQRWQ
2286
RREIS
2291
NFEYL
2296
MFLNT
2301
IAGRT
2306
YNDLN
2311
QYPVF
2316
PWVLT
2321
NYESE
2326
ELDLT
2331
LPGNF
2336
RDLSK
2341
PIGAL
2346
NPKRA
2351
VFYAE
2356
RYETW
2361
EDDQS
2366
PPYHY
2371
NTHYS
2376
TATST
2381
LSWLV
2386
RIEPF
2391
TTFFL
2396
NANDG
2401
KFDHP
2406
DRTFS
2411
SVARS
2416
WRTSQ
2421
RDTSD
2426
VKELI
2431
PEFYY
2436
LPEMF
2441
VNSNG
2446
YNLGV
2451
REDEV
2456
VVNDV
2461
DLPPW
2466
AKKPE
2471
DFVRI
2476
NRMAL
2481
ESEFV
2486
SCQLH
2491
QWIDL
2496
IFGYK
2501
QRGPE
2506
AVRAL
2511
NVFHY
2516
LTYEG
2521
SVNLD
2526
SITDP
2531
VLREA
2536
MEAQI
2541
QNFGQ
2546
TPSQL
2551
LIEPH
2556
PPRSS
2561
AMHLC
2566
FLPQS
2571
PLMFK
2576
DQMQQ
2581
DVIMV
2586
LKFPS
2591
NSPVT
2596
HVAAN
2601
TLPHL
2606
TIPAV
2611
VTVTC
2616
SRLFA
2621
VNRWH
2626
NTVGL
2631
RGAPG
2636
YSLDQ
2641
AHHLP
2646
IEMDP
2651
LIANN
2656
SGVNK
2661
RQITD
2666
LVDQS
2671
IQINA
2676
HCFVV
2681
TADNR
2686
YILIC
2691
GFWDK
2696
SFRVY
2701
STETG
2706
KLTQI
2711
VFGHW
2716
DVVTC
2721
LARSE
2726
SYIGG
2731
DCYIV
2736
SGSRD
2741
ATLLL
2746
WYWSG
2751
RHHII
2756
GDNPN
2761
SSDYP
2766
APRAV
2771
LTGHD
2776
HEVVC
2781
VSVCA
2786
ELGLV
2791
ISGAK
2796
EGPCL
2801
VHTIT
2806
GDLLR
2811
ALEGP
2816
ENCLF
2821
PRLIS
2826
VSSEG
2831
HCIIY
2836
YERGR
2841
FSNFS
2846
INGKL
2851
LAQME
2856
INDST
2861
RAILL
2866
SSDGQ
2871
NLVTG
2876
GDNGV
2881
VEVWQ
2886
ACDFK
2891
QLYIY
2896
PGCDA
2901
GIRAM
2906
DLSHD
2911
QRTLI
2916
TGMAS
2921
GSIVA
2926
FNIDF
2931
NRWHY
2936
EHQNR
2941
Y
2946
Mutation Information
DNA mutation:
None
Peptide Range:
1112 ~ 1136
Mut AA position:
1124 (13 in Wild Type peptide)
Alignment
Wild Type:
"HGSVGIIKKNEEKDNGPLITLADEK
||||||||||||.||||||||||||
Mutant:
HGSVGIIKKNEENDNGPLITLADEK"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) NBEA
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay