Immunogenicity 9079

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CLIC6
Transcript ID
NM_053277
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (686 aa)
MAEAA
1
EPEGV
6
APGPQ
11
GPPEV
16
PAPLA
21
ERPGE
26
PGAAG
31
GEAEG
36
PEGSE
41
GAEEA
46
PRGAA
51
AVKEA
56
GGGGP
61
DRGPE
66
AEARG
71
TRGAH
76
GETEA
81
EEGAP
86
EGAEV
91
PQGGE
96
ETSGA
101
QQVEG
106
ASPGR
111
GAQGE
116
PRGEA
121
QREPE
126
DSAAP
131
ERQEE
136
AEQRP
141
EVPEG
146
SASGE
151
AGDSV
156
DAEGP
161
LGDNI
166
EAEGP
171
AGDSV
176
EAEGR
181
VGDSV
186
DAEGP
191
AGDSV
196
DAEGP
201
LGDNI
206
QAEGP
211
AGDSV
216
DAEGR
221
VGDSV
226
DAEGP
231
AGDSV
236
DAEGR
241
VGDSV
246
EAGDP
251
AGDGV
256
EAGVP
261
AGDSV
266
EAEGP
271
AGDSM
276
DAEGP
281
AGRAR
286
RVSGE
291
PQQSG
296
DGSLS
301
PQAEA
306
IEVAA
311
GESAG
316
RSPGE
321
LAWDA
326
AEEAE
331
VPGVK
336
GSEEA
341
APGDA
346
RADAG
351
EDRVG
356
DGPQQ
361
EPGED
366
EERRE
371
RSPEG
376
PREEE
381
AAGGE
386
EESPD
391
SSPHG
396
EASRG
401
AAEPE
406
AQLSN
411
HLAEE
416
GPAEG
421
SGEAA
426
RVNGR
431
REDGE
436
ASEPR
441
ALGQE
446
HDITL
451
FVKAG
456
YDGES
461
IGNCP
466
FSQRL
471
FMILW
476
LKGVI
481
FNVTT
486
VDLKR
491
KPADL
496
QNLAP
501
GTNPP
506
FMTFD
511
GEVKT
516
DVNKI
521
EEFLE
526
EKLAP
531
PRYPK
536
LGTQH
541
PESNS
546
AGNDV
551
FAKFS
556
AFIKN
561
TKKDA
566
NEIHE
571
KNLLK
576
ALRKL
581
DNYLN
586
SPLPD
591
EIDAY
596
STEDV
601
TVSGR
606
KFLDG
611
DELTL
616
ADCNL
621
LPKLH
626
IIKIV
631
AKKYR
636
DFEFP
641
SEMTG
646
IWRYL
651
NNAYA
656
RDEFT
661
NTCPA
666
DQEIE
671
HAYSD
676
VAKRM
681
K
686
Mutation Information
DNA mutation:
None
Peptide Range:
213 ~ 238
Mut AA position:
225 (13 in Wild Type peptide)
Alignment
Wild Type:
"EGPAGDSVDAEGRVGDSVDAEGPAG-
||||||||||||..|||||||||||
Mutant:
EGPAGDSVDAEGPAGDSVDAEGPAGD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CLIC6

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay