Immunogenicity 915
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PWWP2B
Transcript ID
ENST00000305233
HLA INFO
DRB*03:01
TCR INFO
No TCR info found!
Full length protein sequence (590 aa)
MEPRA
1
GCRLP
6
VRVEQ
11
VVNGA
16
LVVTV
21
SCGER
26
SFAGI
31
LLDCT
36
KKSGL
41
FGLPP
46
LAPLP
51
QVDES
56
PVNDS
61
HGRAP
66
EEGDA
71
EVMQL
76
GSSSP
81
PPARG
86
VQPPE
91
TTRPE
96
PPPPL
101
VPPLP
106
AGSLP
111
PYPPY
116
FEGAP
121
FPHPL
126
WLRDT
131
YKLWV
136
PQPPP
141
RTIKR
146
TRRRL
151
SRNRD
156
PGRLI
161
LSTIR
166
LRPRQ
171
VLCEK
176
CKSTL
181
SPPEA
186
SPGPP
191
AAPRA
196
RRRLG
201
SGPDR
206
ELRKP
211
EEPEN
216
GEPTA
221
AATAR
226
RSKRE
231
RREED
236
RAPAE
241
QVPRS
246
PVIKI
251
SYSTP
256
QGKGE
261
VVKIP
266
SRVHG
271
SLEPF
276
RPQQA
281
PQDDG
286
SQDPE
291
VLDRE
296
SRDRP
301
SCAPS
306
ASIPK
311
LKLTR
316
PVPAG
321
ADLPP
326
PKIRL
331
KPHRL
336
GDSEH
341
EPVYR
346
AELVG
351
ELNGY
356
LRDSS
361
PAPCA
366
DGPAG
371
GLADL
376
SSGSS
381
GEDDD
386
FKSCP
391
QGPQG
396
REGLA
401
FLVSC
406
PEGRA
411
DCASE
416
SACSS
421
DSLDE
426
ARSSG
431
SEGTP
436
ADTGD
441
LSPGH
446
GASAP
451
SVSRE
456
ARQTV
461
PPLTV
466
RLHTQ
471
SVSEC
476
ITEDG
481
RTVAV
486
GDIVW
491
GKIHG
496
FPWWP
501
ARVLD
506
ISLGQ
511
KEDGE
516
PSWRE
521
AKVSW
526
FGSPT
531
TSFLS
536
ISKLS
541
PFSEF
546
FKLRF
551
NRKKK
556
GMYRK
561
AITEA
566
ANAAR
571
HVAPE
576
IRELL
581
TQFET
586
Mutation Information
DNA mutation:
None
Peptide Range:
77 ~ 101
Mut AA position:
89 (13 in Wild Type peptide)
Alignment
Wild Type:
"VMQLGSSSPPPARGVQPPETTRPEP
||||||||||||.||||||||||||
Mutant:
VMQLGSSSPPPACGVQPPETTRPEP"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PWWP2B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay